Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog.
about
Notum deacylates Wnt proteins to suppress signalling activityModular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1The Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolutionDifferential range and activity of various forms of the Hedgehog proteinGgamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration.Genetic and biochemical definition of the Hedgehog receptor.Coexpression of SFRP1 and WIF1 as a prognostic predictor of favorable outcomes in patients with colorectal carcinoma.The role of glypicans in Wnt inhibitory factor-1 activity and the structural basis of Wif1's effects on Wnt and Hedgehog signaling.Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless.Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.A fully human inhibitory monoclonal antibody to the Wnt receptor RYKWnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.Extracellular movement of signaling molecules.Heparan sulphate proteoglycans: the sweet side of development.Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development.The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.Patched, the receptor of Hedgehog, is a lipoprotein receptor.Quantification of ortholog losses in insects and vertebrates.Lipid modification of secreted signaling proteins.Targeting Drosophila eye developmentAbsolute requirement of cholesterol binding for Hedgehog gradient formation in Drosophila.Role of the ABC transporter Mdr49 in Hedgehog signaling and germ cell migration.The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity.The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migrationAcyltransferases for secreted signalling proteins (Review).Shaping morphogen gradients by proteoglycansHox targets and cellular functionsInteractions between Hedgehog proteins and their binding partners come into view.Morphogen gradients in development: from form to function.DSulfatase-1 fine-tunes Hedgehog patterning activity through a novel regulatory feedback loop.Isolation and characterization of a secreted, cell-surface glycoprotein SCUBE2 from humans.Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs.Cells on the move: Modulation of guidance cues during germ cell migration.Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing.Developmental biology: morphogens hitch a greasy ride.From top to bottom: Cell polarity in Hedgehog and Wnt trafficking.Perspectives on Intra- and Intercellular Trafficking of Hedgehog for Tissue Patterning.Quantitative Morphological Variation in the Developing Drosophila Wing.Gene expression analysis of potential morphogen signalling modifying factors in Panarthropoda
P2860
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P2860
Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@en
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@nl
type
label
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@en
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@nl
prefLabel
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@en
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@nl
P2093
P1433
P1476
Shifted, the Drosophila orthol ...... tion and movement of Hedgehog.
@en
P2093
Alain Vincent
Bruno Glise
Catherine A Miller
David J Olson
Michael A Halbisen
Michèle Crozatier
Seth S Blair
Steve Wise
P304
P356
10.1016/J.DEVCEL.2005.01.003
P407
P577
2005-02-01T00:00:00Z