The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation.
about
Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.A conformational switch underlies ClpP protease functionStructural Switching of Staphylococcus aureus Clp Protease: A KEY TO UNDERSTANDING PROTEASE DYNAMICSStructural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparumInsights into Structural Network Responsible for Oligomerization and Activity of Bacterial Virulence Regulator Caseinolytic Protease P (ClpP) ProteinHelix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp ProteaseStructural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triadMolecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulationBinding of the ClpA unfoldase opens the axial gate of ClpP peptidaseLocal and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations.The ClpP N-terminus coordinates substrate access with protease active site reactivity.Quantitative NMR spectroscopy of supramolecular complexes: dynamic side pores in ClpP are important for product releaseClpXP, an ATP-powered unfolding and protein-degradation machineMixtures of opposing phosphorylations within hexamers precisely time feedback in the cyanobacterial circadian clockComparison of the multiple oligomeric structures observed for the Rvb1 and Rvb2 proteins.AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.Impact of the N-terminal amino acid on targeted protein degradation.The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease.The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1Turned on for degradation: ATPase-independent degradation by ClpP.The purification of the Chlamydomonas reinhardtii chloroplast ClpP complex: additional subunits and structural featuresClpP: a distinctive family of cylindrical energy-dependent serine proteases.Degradation of SsrA-tagged proteins in streptococci.An overview of molecular stress response mechanisms in Escherichia coli contributing to survival of Shiga toxin-producing Escherichia coli during raw milk cheese production.Dynamics of the ClpP serine protease: a model for self-compartmentalized proteases.Mini review: ATP-dependent proteases in bacteria.The development of small-molecule modulators for ClpP protease activity.Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease.Control of substrate gating and translocation into ClpP by channel residues and ClpX binding.Structural determinants stabilizing the axial channel of ClpP for substrate translocation.Large nucleotide-dependent movement of the N-terminal domain of the ClpX chaperone.Substrate delivery by the AAA+ ClpX and ClpC1 unfoldases activates the mycobacterial ClpP1P2 peptidaseInteraction specificity between the chaperone and proteolytic components of the cyanobacterial Clp protease.Topology of the VirB4 C terminus in the Agrobacterium tumefaciens VirB/D4 type IV secretion system.Downregulation of ClpR2 leads to reduced accumulation of the ClpPRS protease complex and defects in chloroplast biogenesis in Arabidopsis.Perrault syndrome type 3 caused by diverse molecular defects in CLPP
P2860
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P2860
The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@en
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@nl
type
label
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@en
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@nl
prefLabel
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@en
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@nl
P2093
P2860
P356
P1476
The ClpP double ring tetradeca ...... P and ClpAP complex formation.
@en
P2093
Anna Gribun
Klaus M Fiebig
Matthew S Kimber
Reagan Ching
Remco Sprangers
Walid A Houry
P2860
P304
16185-16196
P356
10.1074/JBC.M414124200
P407
P577
2005-02-08T00:00:00Z