IL-4-producing CD8+ T cells with a CD62L++(bright) phenotype accumulate in a subgroup of older adults and are associated with the maintenance of intact humoral immunity in old age.
about
Immunosenescence and vaccination.A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis.Effects of aging on the adaptive immune response to respiratory virus infections.Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.NK-like T cells and plasma cytokines, but not anti-viral serology, define immune fingerprints of resilience and mild disability in exceptional aging.Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells.Profiling the CD8low phenotype, an alternative career choice for CD8 T cells during primary differentiation.Is Immune Aging a Cause of Disease among the Elderly, or is it a Passive Indicator of General Decline of Physiologic Function?Integration of immunity with physical and cognitive function in definitions of successful aging.Non-malignant clonal expansions of CD8+ memory T cells in aged individuals.Lower GrB+ CD62Lhigh CD8 TCM effector lymphocyte response to influenza virus in older adults is associated with increased CD28null CD8 T lymphocytes.Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates.Immunizations in the elderly: do they live up to their promise?An altered relationship of influenza vaccine-specific IgG responses with T cell immunity occurs with aging in humans.An oral recombinant Salmonella enterica serovar Typhimurium mutant elicits systemic antigen-specific CD8+ T cell cytokine responses in miceGain and loss of T cell subsets in old age--age-related reshaping of the T cell repertoire.Expression of γ-chain cytokine receptors on CD8+ T cells in HIV infection with a focus on IL-7Rα (CD127).Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments.How to define biomarkers of human T cell aging and immunocompetence?Immunosenescence in aging: between immune cells depletion and cytokines up-regulation.Autoreactive human peripheral blood CD8+ T cells with a regulatory phenotype and function.How to fit allergen immunotherapy in the elderly.
P2860
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P2860
IL-4-producing CD8+ T cells with a CD62L++(bright) phenotype accumulate in a subgroup of older adults and are associated with the maintenance of intact humoral immunity in old age.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
IL-4-producing CD8+ T cells with a CD62L++
@nl
IL-4-producing CD8+ T cells wi ...... t humoral immunity in old age.
@en
type
label
IL-4-producing CD8+ T cells with a CD62L++
@nl
IL-4-producing CD8+ T cells wi ...... t humoral immunity in old age.
@en
prefLabel
IL-4-producing CD8+ T cells with a CD62L++
@nl
IL-4-producing CD8+ T cells wi ...... t humoral immunity in old age.
@en
P2093
P1476
IL-4-producing CD8+ T cells wi ...... t humoral immunity in old age.
@en
P2093
Anna Maria Wolf
Brigitte Jenewein
Peter Robatscher
Susanne Schwaiger
P304
P356
10.4049/JIMMUNOL.170.1.613
P407
P577
2003-01-01T00:00:00Z