The effects of mutation on the regulatory properties of phospholamban in co-reconstituted membranes.
about
Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathySuperinhibitory phospholamban mutants compete with Ca2+ for binding to SERCA2a by stabilizing a unique nucleotide-dependent conformational state.Phospholamban C-terminal residues are critical determinants of the structure and function of the calcium ATPase regulatory complex.Interactions between Ca2+-ATPase and the pentameric form of phospholamban in two-dimensional co-crystalsPhosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pumpPhospholamban phosphorylation, mutation, and structural dynamics: a biophysical approach to understanding and treating cardiomyopathy.Regulation of the sarcoplasmic reticulum calcium pump by divergent phospholamban isoforms in zebrafish.Atomic-level mechanisms for phospholamban regulation of the calcium pump.Transmembrane helix 11 is a genuine regulator of the endoplasmic reticulum Ca2+ pump and acts as a functional parallel of β-subunit on α-Na+,K+-ATPase.Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A.Activating and deactivating roles of lipid bilayers on the Ca(2+)-ATPase/phospholamban complexSarco(endo)plasmic reticulum calcium ATPase (SERCA) inhibition by sarcolipin is encoded in its luminal tail.Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer.Conformational memory in the association of the transmembrane protein phospholamban with the sarcoplasmic reticulum calcium pump SERCA.
P2860
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P2860
The effects of mutation on the regulatory properties of phospholamban in co-reconstituted membranes.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
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2005年學術文章
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name
The effects of mutation on the ...... in co-reconstituted membranes.
@en
The effects of mutation on the ...... in co-reconstituted membranes.
@nl
type
label
The effects of mutation on the ...... in co-reconstituted membranes.
@en
The effects of mutation on the ...... in co-reconstituted membranes.
@nl
prefLabel
The effects of mutation on the ...... in co-reconstituted membranes.
@en
The effects of mutation on the ...... in co-reconstituted membranes.
@nl
P2093
P356
P1433
P1476
The effects of mutation on the ...... in co-reconstituted membranes
@en
P2093
Howard S Young
Jennifer L Douglas
Michael Afara
P304
P356
10.1021/BI047878D
P407
P577
2005-03-01T00:00:00Z