Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease.
about
Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical ImplicationsCurrent status of PET imaging in Huntington's diseaseBiallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in InfancyMolecular Imaging Markers to Track Huntington’s Disease PathologyStriatal phosphodiesterase 10A and medial prefrontal cortical thickness in patients with schizophrenia: a PET and MRI studyStriatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease miceProgressive Cl- channel defects reveal disrupted skeletal muscle maturation in R6/2 Huntington's mice.PET Imaging in Huntington's Disease.Cognitive dysfunction in Huntington's disease: mechanisms and therapeutic strategies beyond BDNF.Phosphodiesterase 10 inhibitors in clinical development for CNS disorders.Investigational agents for the management of Huntington's disease.Huntington Disease: Linking Pathogenesis to the Development of Experimental Therapeutics.Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice.Regulation of Striatal Neuron Activity by Cyclic Nucleotide Signaling and Phosphodiesterase Inhibition: Implications for the Treatment of Parkinson's Disease.TAK-063, a novel PDE10A inhibitor with balanced activation of direct and indirect pathways, provides a unique opportunity for the treatment of schizophrenia.Brain PET measurement of PDE10A occupancy by TAK-063, a new PDE10A inhibitor, using [11 C]T-773 in nonhuman primates.In vivo characterization of two 18F-labeled PDE10A PET radioligands in nonhuman primate brains.Inhibition of Adrenergic and Non-Adrenergic Smooth Muscle Contraction in the Human Prostate by the Phosphodiesterase 10-Selective Inhibitor TC-E 5005.Neuroimaging of Sleep Disturbances in Movement Disorders
P2860
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P2860
Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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name
Altered PDE10A expression dete ...... onset in Huntington's disease.
@en
Altered PDE10A expression dete ...... onset in Huntington's disease.
@nl
type
label
Altered PDE10A expression dete ...... onset in Huntington's disease.
@en
Altered PDE10A expression dete ...... onset in Huntington's disease.
@nl
prefLabel
Altered PDE10A expression dete ...... onset in Huntington's disease.
@en
Altered PDE10A expression dete ...... onset in Huntington's disease.
@nl
P2093
P2860
P50
P356
P1433
P1476
Altered PDE10A expression dete ...... onset in Huntington's disease.
@en
P2093
Andri C Tziortzi
Eugenii A Rabiner
Flavia Niccolini
Graham E Searle
Marios Politis
Paola Piccini
Salman Haider
Shitij Kapur
P2860
P304
P356
10.1093/BRAIN/AWV214
P407
P577
2015-07-21T00:00:00Z