Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. - Wikidata - awgldk - TriplyDB

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.

http://www.wikidata.org/entity/Q45310539

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Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice Immunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.Drug Development in Alzheimer's Disease: The Contribution of PET and SPECT Emerging Link between Alzheimer's Disease and Homeostatic Synaptic Plasticity Dysregulation of glutathione homeostasis in neurodegenerative diseases Alzheimer's therapeutics: translation of preclinical science to clinical drug development Reevaluating Metabolism in Alzheimer's Disease from the Perspective of the Astrocyte-Neuron Lactate Shuttle Model GABA(A) receptor-mediated acceleration of aging-associated memory decline in APP/PS1 mice and its pharmacological treatment by picrotoxin Diminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease Mice A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models An aqueous orally active vaccine targeted against a RAGE/AB complex as a novel therapeutic for Alzheimer's disease Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss.APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD).Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor.Modeling an anti-amyloid combination therapy for Alzheimer's disease.BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.Amyloid precursor protein increases cortical neuron size in transgenic mice Inhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid balance and spatial memory in mice.Alzheimer disease models and human neuropathology: similarities and differences Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.A longitudinal study of cognition, proton MR spectroscopy and synaptic and neuronal pathology in aging wild-type and AβPPswe-PS1dE9 mice Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease.Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.Cardiomyocyte contractile dysfunction in the APPswe/PS1dE9 mouse model of Alzheimer's disease Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice.APPswe/PS1dE9 mice with cortical amyloid pathology show a reduced NAA/Cr ratio without apparent brain atrophy: A MRS and MRI study 17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice.Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development A novel Alzheimer's disease drug candidate targeting inflammation and fatty acid metabolism.Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 mice Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2).Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome Gene-environment interaction research and transgenic mouse models of Alzheimer's disease.Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks.A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease

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Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.

http://www.wikidata.org/entity/Q45310539

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年學術文章

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Episodic-like memory deficits ...... eurotransmitter abnormalities.

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Episodic-like memory deficits ...... eurotransmitter abnormalities.

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type

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Episodic-like memory deficits ...... eurotransmitter abnormalities.

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Episodic-like memory deficits ...... eurotransmitter abnormalities.

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Episodic-like memory deficits ...... eurotransmitter abnormalities.

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J.NBD.2004.10.022

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Neurobiology of Disease

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Alena Savonenko

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Alicja L Markowska

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David R Borchelt

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Fai Tang

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Alzheimer's disease

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