about
TP53 binds the TIGAR geneTP53 stimulates TIGAR expressionTIGAR converts D-fructose-2;6-bisphosphate to D-fructose 6-phosphateD-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphatealpha-D-glucose 6-phosphate + NADP+ => D-glucono-1;5-lactone 6-phosphate + NADPH + H+TP53 binds the PTEN promoterPTEN gene transcription is stimulated by TP53miR-26A microRNAs bind PTEN mRNAPTEN mRNA translation negatively regulated by microRNAsTP53 binds regulatory elements of SESN1;2;3 genesTP53 stimulates expression of SESN1;2;3 genesPRDX1 overoxidizesSESN1;2;3 bind overoxidized PRDX1p-AMPK phosphorylates TSC1:TSC2RHEB in mTORC1:RHEB:GTP hydrolyses GTPSESN1;2;3 bind AMPKTP63/TP53 bind the DDIT4 gene promoterTP63/TP53 stimulates transcription of DDIT4 geneFormation of TSC1:TSC2 complexAKT phosphorylates TSC2; inhibiting itp-S939;T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4DDIT4 binds 14-3-3 dimerTP53 binds the SCO2 geneTP53 stimulates SCO2 gene transcriptionElectron transfer from reduced cytochrome c to molecular oxygenTP53 binds the RRM2B geneTP53 stimulates transcription of RRM2B geneTP53 binds the GLS2 promoterTP53 stimulates GLS2 transcriptionglutamine + H2O => glutamate + NH4+
P361
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P361
description
An instance of the biological pathway TP53 Regulates Metabolic Genes in Homo sapiens
@en
name
TP53 Regulates Metabolic Genes
@en
type
label
TP53 Regulates Metabolic Genes
@en
prefLabel
TP53 Regulates Metabolic Genes
@en
P2860
P527
P2860
P3937
R-HSA-5628897