about
Formation of MHC II alpha beta heterodimerInteraction of invariant chain trimer and MHC II alpha beta dimerFormation of nonameric complexDissociation of CANX from nonameric complexFormation of COPII vesicleFusion of COPII vesicle with Golgi complexTransport of MHC II:Ii complex along Golgi to TGNTGN-lysosomal vesicle coat assemblyDissociation of Arf1:GDP; AP-1 Clathrin coated nonameric complexTranslocation of TGN-lysosome vesicle to lysosomeTGN-lysosome vesicle uncoating and release of nonameric complex to lysosomeTransport of MHC II:Ii complex to plasma membraneInsertion of MHC II:Ii complex in to the plasma membraneRecruitment of clathrin coated vesicle by IiInternalization of MHC II:Ii clathrin coated vesicleUncoating of clathrin-coated vesicles and fusion with endosomesTrafficking of nonameric complex in the endocytic pathwayInitial proteolyis of Ii by aspartic proteases to lip22Cleavage of lip22 to lip10Generation of CLIP from lip10Disassociation of CLIP from MHC IIMHC class II antigen internalizationReduction of disulphide bonds in MHC II antigensMHC class II antigen processingLoading of antigenic peptidesTransport of antigen loaded MHC II molecules to surfaceLAG3 (CD233) binds MHC II
P361
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P361
description
An instance of the biological pathway MHC class II antigen presentation in Homo sapiens
@en
name
MHC class II antigen presentation
@en
type
label
MHC class II antigen presentation
@en
prefLabel
MHC class II antigen presentation
@en
P2860
P527
P2860
P31
P3937
R-HSA-2132295