about
Beta-catenin phosphorylation cascadeRepression of WNT target genesExpression of AMER1 geneExpression of AXIN1 geneAPC is K63-polyubiquitinatedAssembly of the destruction complexAXIN is phosphorylated in the destruction complexAssociation of beta-catenin with the destruction complexPhosphorylation of APC component of the destruction complexDissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complexAssociation of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complexMulti-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)Degradation of ubiquitinated beta catenin by the proteasome
P361
P527
Q45318244-C737E914-4643-4C7A-9CB1-F39314810B65Q45318245-C5692413-70BC-4E47-A34D-E04EE465F301Q50298704-F5838896-C137-4B6A-A747-4F1E9ADE7A06Q50298705-43BA9145-2683-4488-A325-B897DF9157BFQ50298706-981C279B-BA8E-455C-8365-FE3E7AC54475Q50298707-EB2F96CB-2D6F-469D-BD42-3EE095558BADQ50298708-FCB4FCC8-4F09-4867-A18E-1CC8457D09CEQ50298710-85111700-47BF-4ED2-A839-252366D348FAQ50298715-0458690A-8939-42FF-944E-2A5B78D94C33Q50298716-6781FF5A-45DD-4BCB-B85E-6F73B6EE99DFQ50298717-199D949D-8DCB-4032-BEF7-E35D174BCAC4Q50298718-FD0D37D3-D1F3-413B-9349-0FA2D02DABBFQ50298720-FE91F3BF-A169-4209-8E52-106F71DDE14E
P361
description
An instance of the biological ...... uction complex in Homo sapiens
@en
name
Degradation of beta-catenin by the destruction complex
@en
type
label
Degradation of beta-catenin by the destruction complex
@en
prefLabel
Degradation of beta-catenin by the destruction complex
@en
P527
P361
P3937
R-HSA-195253