GLI3 is processed to GLI3R by the proteasome - Wikidata - awgldk - TriplyDB

GLI3 is processed to GLI3R by the proteasome

GLI3 is processed to GLI3R by the proteasome

http://www.wikidata.org/entity/Q45318273

about

PKA phosphorylates GLI3 CK1 phosphorylates p-GLI3 GSK3 phosphorylates p-GLI3 SCF(beta-TrCP) ubiquitinates p-GLI3 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor

P361

Hedgehog 'off' state

P527

Q50298927-657F0F23-4C5E-4A6A-9682-103165C8AC49 Q50298928-E73323AF-87D3-4194-9EBB-0B65874FE931 Q50298929-749E79CB-DF11-42BD-8016-BC8B2E33146B Q50298930-2E34E2D0-1793-4B06-9808-DAEB308A56BE Q50298931-F019E0AF-D6A1-491F-B310-BC13F00E6E1A

P361

Q45318271-DA6C217D-C687-4579-98BE-591B1B550776

P527

GLI3 is processed to GLI3R by the proteasome

http://www.wikidata.org/entity/Q45318273

description

An instance of the biological ...... the proteasome in Homo sapiens

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name

GLI3 is processed to GLI3R by the proteasome

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type

label

GLI3 is processed to GLI3R by the proteasome

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prefLabel

GLI3 is processed to GLI3R by the proteasome

@en

P2860

Q45318273-1E45EB48-37B7-4414-A464-8D89BF5C453F

Q45318273-20FBA1F6-CC9B-4471-BF72-71B62A76B731

Q45318273-26F4D906-DA19-4B37-9286-C2E2EDF8E9F5

Q45318273-5F596269-6424-4E77-9D0F-27429AE461C1

Q45318273-8B415C2A-382A-481A-8A73-21496E75FD25

Q45318273-C0251513-6166-4C5F-A9BE-222E08B36AC7

P2888

Q45318273-07AFC53A-2764-496C-AB4F-DEB1322926A9

P31

Q45318273-4BA7A600-8F4F-4D0F-B183-D3202389AE71

P361

Q45318273-FC37232E-F3D9-4CE1-8997-40B4B98A1933

P3937

Q45318273-2491E0AE-6E71-48CF-8C59-538FBB8A5744

P527

Q45318273-28F158A0-383D-4E9D-83D0-458204509E5F

Q45318273-5FC34609-1B28-4923-A0DF-2AAC0AB0C082

Q45318273-611FF9F0-A0B1-4E32-B5E6-6205F3D9AEB3

Q45318273-88EF44C5-11D2-4794-9358-BD72D829D6EC

Q45318273-98A3F8F6-8D96-46EB-8DD5-738A0E35AC8B

P703

Q45318273-0DF36BCE-BB90-463D-BF2E-A5252DF9B5A9

P2860

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome.

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.

Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.

P2888

reactome:R-HSA-5610785

P31

biological pathway

P361

Hedgehog 'off' state

P3937

R-HSA-5610785

http://www.w3.org/2001/XMLSchema#string

P527

PKA phosphorylates GLI3

CK1 phosphorylates p-GLI3

GSK3 phosphorylates p-GLI3

SCF(beta-TrCP) ubiquitinates p-GLI3

GLI3 is partially degraded by the proteasome to yield the GLI3 repressor

P703