The processivity of multiubiquitination by the APC determines the order of substrate degradation.
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The function of APC/CCdh1 in cell cycle and beyondThe mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2PP2A delays APC/C-dependent degradation of separase-associated but not free securinPhosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phaseDeubiquitinases sharpen substrate discrimination during membrane protein degradation from the ERMechanism of ubiquitin-chain formation by the human anaphase-promoting complexNovel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7A feeling for the numbers in biologyUbiquitin-Mediated Degradation of Aurora KinasesThe Non-Canonical Role of Aurora-A in DNA ReplicationK11-linked ubiquitin chains as novel regulators of cell divisionShort linear motifs - ex nihilo evolution of protein regulationPost-Translational Modification Profiling--a High-Content Assay for Identifying Protein Modifications in Mammalian Cellular SystemsQuantitative framework for ordered degradation of APC/C substrates.Expression of constitutively active CDK1 stabilizes APC-Cdh1 substrates and potentiates premature spindle assembly and checkpoint function in G1 cellsSpatial reorganization of the endoplasmic reticulum during mitosis relies on mitotic kinase cyclin A in the early Drosophila embryoSequential replication-coupled destruction at G1/S ensures genome stability.Unique D box and KEN box sequences limit ubiquitination of Acm1 and promote pseudosubstrate inhibition of the anaphase-promoting complexA putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete developmentAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayTargeting proteins for degradationUbiquitination and degradation of the inhibitors of NF-kappaBThe eukaryotic linear motif resource ELM: 10 years and countingThe APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exitCell-fate determination by ubiquitin-dependent regulation of translationBuilding ubiquitin chains: E2 enzymes at workAurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.Differential regulation of anaphase promoting complex/cyclosome substrates by the spindle assembly checkpoint in Saccharomyces cerevisiae.Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes.Microtubule-dependent regulation of mitotic protein degradation.Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer.UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complexEnhanced protein degradation by branched ubiquitin chains.Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding.RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.The coupling of pathways and processes through shared components.Elucidating the in vivo phosphorylation dynamics of the ERK MAP kinase using quantitative proteomics data and Bayesian model selection.Paradigms of protein degradation by the proteasome.Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer.
P2860
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P2860
The processivity of multiubiquitination by the APC determines the order of substrate degradation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
The processivity of multiubiqu ...... rder of substrate degradation.
@en
The processivity of multiubiqu ...... rder of substrate degradation.
@nl
type
label
The processivity of multiubiqu ...... rder of substrate degradation.
@en
The processivity of multiubiqu ...... rder of substrate degradation.
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prefLabel
The processivity of multiubiqu ...... rder of substrate degradation.
@en
The processivity of multiubiqu ...... rder of substrate degradation.
@nl
P1433
P1476
The processivity of multiubiqu ...... order of substrate degradation
@en
P2093
Marc W Kirschner
Sashank K Reddy
P304
P356
10.1016/J.CELL.2005.10.032
P407
P50
P577
2006-01-01T00:00:00Z