Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
about
CED: a conformational epitope databaseCetuximab/C225-induced intracellular trafficking of epidermal growth factor receptorEssential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activityFrom combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathwayEGFR targeted therapy in non-small cell lung cancer: potential role of cetuximabErbB receptors: from oncogenes to targeted cancer therapiesBiological response modifiers in cancerHarnessing the immune system to improve cancer therapyCurrent targeted therapies in the treatment of advanced colorectal cancer: a reviewProfile of panitumumab as first-line treatment in patients with wild-type KRAS metastatic colorectal cancerColon cancer and the epidermal growth factor receptor: Current treatment paradigms, the importance of diet, and the role of chemopreventionProtein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancerImmunotherapy for prostate cancer: recent developments and future challengesStructure-function relationships of ErbB RTKs in the plasma membrane of living cellsCurrent role of EGF receptor monoclonal antibodies and tyrosine kinase inhibitors in the management of head and neck squamous cell carcinomaToward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challengesAcquired resistance to EGFR-targeted therapies in colorectal cancerMonoclonal antibodies for the treatment of cancerEnhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancerThe Chlamydia pneumoniae invasin protein Pmp21 recruits the EGF receptor for host cell entryMatuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for DimerizationAntibodies specifically targeting a locally misfolded region of tumor associated EGFRStructural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor ReceptorStructural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH DomainsIdentification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodiesEnzymatic prenylation and oxime ligation for the synthesis of stable and homogeneous protein-drug conjugates for targeted therapyEpidermal growth factor is a potential biomarker for poor cetuximab response in tongue cancer cells.Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domainAnalyzing and interpreting genome data at the network level with ConsensusPathDBEpidermal growth factor signaling in transformed cellsMechanisms of action of therapeutic antibodies for cancerDesigning nanoconjugates to effectively target pancreatic cancer cells in vitro and in vivoInhibiting the growth of pancreatic adenocarcinoma in vitro and in vivo through targeted treatment with designer gold nanotherapeuticsMagnetic nanoparticles as mediators of ligand-free activation of EGFR signalingPhase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancerIgE-based Immunotherapy of Cancer -A Comparative Oncology ApproachA neutralizing RNA aptamer against EGFR causes selective apoptotic cell deathInhibition of cell proliferation by an anti-EGFR aptamerSingle-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.
P2860
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P2860
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@en
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@nl
type
label
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@en
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@nl
prefLabel
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@en
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@nl
P2093
P1433
P1476
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.
@en
P2093
Jed J W Wiltzius
Karl R Schmitz
Kathryn M Ferguson
Paul Kussie
Philip D Jeffrey
Shiqing Li
P304
P356
10.1016/J.CCR.2005.03.003
P577
2005-04-01T00:00:00Z