Notch signaling controls the generation and differentiation of early T lineage progenitors. - Wikidata - awgldk - TriplyDB

Notch signaling controls the generation and differentiation of early T lineage progenitors.

Notch signaling controls the generation and differentiation of early T lineage progenitors.

http://www.wikidata.org/entity/Q45345206

about

The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development HEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticity Regulatory gene network circuits underlying T cell development from multipotent progenitors Using mouse models to study function of transcriptional factors in T cell development T cell ageing: effects of age on development, survival & function Factors and networks that underpin early hematopoiesis Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis Cbx4 regulates the proliferation of thymic epithelial cells and thymus function Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus GATA-3 is required for early T lineage progenitor development Notch directly regulates Gata3 expression during T helper 2 cell differentiation The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development.Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.Multiple extrathymic precursors contribute to T-cell development with different kinetics.T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.Functional diversity of stem and progenitor cells with B-lymphopoietic potential Progression of regulatory gene expression states in fetal and adult pro-T-cell development.Notch dimerization is required for leukemogenesis and T-cell development.From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation.Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity.Molecular and cellular basis of T cell lineage commitment.E proteins and the regulation of early lymphocyte development Dissecting and circumventing the requirement for RAM in CSL-dependent Notch signaling.Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.Regeneration of the aged thymus by a single transcription factor.Trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis.Microenvironmental niches in the bone marrow required for B-cell development.Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.Emerging strategies to boost thymic function An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene.A critical role for TCF-1 in T-lineage specification and differentiation.

P2860

Q24678633-38BCAE99-67DD-4DDD-AF9D-D4BBBDF65FED Q26822390-3D3AB8F7-BC36-4725-A431-9786D91E052F Q26995184-493D5D5D-2F95-4E93-B3D2-9B2298A86412 Q27011507-28898CB3-F303-460B-9425-3334AD8B7079 Q27015121-A6978418-8548-4F40-A0B8-2DCF6957D532 Q27022335-371C4EBC-B282-4941-945F-591CCE9D3FC6 Q28477072-2EC838F6-A466-4295-A6EB-6F3FCB36B02A Q28504649-C40CBA2A-7B9F-4AFE-B69D-BAA03DD2318E Q28510745-66C27064-580B-427C-BD03-CE66EA189CAB Q28513360-3713F83D-A184-4A0D-854A-A9E27CFDC937 Q28584916-E7724DD8-964D-46ED-8885-D02B212F5EB6 Q28587908-80E0906D-253D-4E41-9B41-A9E29078D268 Q28594834-BDEE32D0-5662-457D-8CD8-AF5ADB7BCD91 Q30157200-5075DCC8-B90A-4E1A-ADC5-BF886472C49A Q33494549-10C42E06-EBFC-4385-ABE6-2AAE06AC2223 Q33677427-F34BE300-CFF2-402E-9F24-562D603C8C4A Q33687647-BD4491A1-65C3-46D7-BA6D-95CDE7016722 Q33722636-214A751F-45B3-497A-9309-091390A4DBA5 Q33885674-5CDE1453-6706-407B-B3CF-0F2C88B2BFA9 Q34083743-A74CEF8C-6A4A-47F5-B278-2E48E7391498 Q34150401-5165E3DE-67F6-42FC-891F-5EB0572F58F3 Q34244256-EAAD688B-7F16-409E-9C0A-228E32FD9137 Q34248553-E382D091-67DD-46CF-9E21-982464498EF0 Q34306829-52C3E107-BCF5-4A63-8B40-089DD9CF563D Q34355912-D753E82F-D31D-45A9-8FD9-B860C1674E99 Q34356462-7BE86EE2-7E30-4884-91D8-C7C61FBC75F5 Q34372409-218ECCFC-F60F-41C1-A3C9-EF7B021716E8 Q34376282-F705D27C-D950-4EFC-A286-230132E0BAB1 Q34414351-CF31016A-48B5-4B8B-AB89-A4E5D289C3B8 Q34489931-E7C08911-2625-45AA-81A2-325D586BC89B Q34496406-68933A72-2EA2-4B17-89A3-B46C2601B01C Q34533121-A526E898-136E-44B4-864A-3FCE017E18A4 Q34707432-75D4EE09-D1EE-4B14-914A-BC825C8C88FB Q34768853-6C11B930-A41F-4FE5-AD9A-1B3E0488FA60 Q34919049-70AB3F46-83B3-4F22-8CDB-0B71ED6314E6 Q34958884-7064DF3E-D3C5-4D79-B62B-B84EB4C42387 Q34998268-4CF2684E-DD49-4814-9AD7-3D22C9201442 Q35069523-3AE5FF35-9DF1-4C2A-B5D7-F88D57DDC29B Q35096281-8C251DAB-29E3-4A33-BD7F-14D9B8BC6CDD Q35165548-109628D1-C013-4509-8B5C-35608AF8A509

P2860

Notch signaling controls the generation and differentiation of early T lineage progenitors.

http://www.wikidata.org/entity/Q45345206

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh-hant

name

Notch signaling controls the g ...... f early T lineage progenitors.

@en

Notch signaling controls the g ...... f early T lineage progenitors.

@nl

type

label

Notch signaling controls the g ...... f early T lineage progenitors.

@en

Notch signaling controls the g ...... f early T lineage progenitors.

@nl

prefLabel

Notch signaling controls the g ...... f early T lineage progenitors.

@en

Notch signaling controls the g ...... f early T lineage progenitors.

@nl

P1433

Q45345206-98B3FE8D-D403-41BD-8BD1-89E7D7288265

P1476

Q45345206-990EE413-3F43-4114-A748-9787C8D3CA97

P2093

Q45345206-2E056E0A-5EA6-4835-9969-06103AE4966F

Q45345206-34C752B1-4FDA-45AE-B3BE-71177BCE22B6

Q45345206-56E7230D-4F54-4F09-8CF3-21C32CFED8AB

Q45345206-6E1F1D26-9075-4DA8-B610-A936FDF71035

Q45345206-7D831A6A-FCB6-4EB0-8496-E52973A8D7FC

Q45345206-9DC1BCE8-339B-4526-B341-2ABCF824669F

Q45345206-C1FE19E9-6AC3-4C64-A839-5D0AD686F21B

Q45345206-F009E10E-2F21-4443-B4E1-0DCE796508CA

P2860

Q45345206-0BFE44D1-E15B-4206-8873-F130EEF2C8AD

Q45345206-152B0B64-38A1-47BB-BAAE-7A03CD5F23E2

Q45345206-1CBD0766-9DA7-4A97-8B1F-43BCF4DD22B0

Q45345206-22BD7297-AE5C-4183-ABA7-603231B21DFE

Q45345206-28C209AF-EB4B-4143-A604-12B4492460E7

Q45345206-32F1A64B-0E78-48B3-9C0A-F07EC87BBCC4

Q45345206-33DC2F14-EE3B-4EA4-B382-FA9AC6CA9B8F

Q45345206-34361D99-B6D0-4C7D-A4A9-14371A6E9FCE

Q45345206-46DE07BB-69C1-440F-B92B-DF92E775FE27

Q45345206-4A85205E-5C53-4C35-B09B-A4C1AB321665

P2888

Q45345206-D0D0AFDC-A330-4B72-86BB-B73880785518

P304

Q45345206-78EC1246-A367-4C1E-AF5C-533429CC7228

P31

Q45345206-E14FE53C-BEBE-4119-876F-C2EA2740BB3B

P356

Q45345206-62853141-3BDB-4313-BDD4-1F171FC1CE3B

P407

Q45345206-89133E86-00D0-468B-B6EA-7B8007836E40

P433

Q45345206-3D843180-8AFE-4EAA-AA73-796E5A699A10

P478

Q45345206-B920385D-5474-4701-A5CF-E82EAB58EE74

P577

Q45345206-55661EEC-F402-4DA3-8472-A8ECA6F2A350

P5875

Q45345206-17368DB7-9B02-4E83-8D23-BC65D645111F

P6179

Q45345206-18F48506-B787-43EE-8310-4AEEA906D5B0

P698

Q45345206-BF2CDACD-0FCA-490D-AF4F-13EE40895452

P356

P1433

Nature Immunology

P1476

Notch signaling controls the g ...... f early T lineage progenitors.

@en

P2093

Arivazhagan Sambandam

http://www.w3.org/2001/XMLSchema#string

Avinash Bhandoola

http://www.w3.org/2001/XMLSchema#string

Ivan Maillard

http://www.w3.org/2001/XMLSchema#string

Jon C Aster

http://www.w3.org/2001/XMLSchema#string

Lanwei Xu

http://www.w3.org/2001/XMLSchema#string

Rachel M Gerstein

http://www.w3.org/2001/XMLSchema#string

Valerie P Zediak

http://www.w3.org/2001/XMLSchema#string

Warren S Pear

http://www.w3.org/2001/XMLSchema#string

P2860

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

Transcription factor GATA-3 is required for development of the T-cell lineage

Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development.

L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor.

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling.

P2888

P304

663-670

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NI1216

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P577

2005-06-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7790513

http://www.w3.org/2001/XMLSchema#string

P6179

1043382175

http://www.w3.org/2001/XMLSchema#string

P698

15951813

http://www.w3.org/2001/XMLSchema#string