NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome.
about
Emerging roles for the influenza A virus nuclear export protein (NEP)Nucleocytoplasmic shuttling of influenza A virus proteinsThe interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replicationA Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNAA novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferonViral factors in influenza pandemic risk assessment.Possibility of cross-species/subtype reassortments in influenza A viruses: an analysis of nonstructural protein variations.Conserved features of the PB2 627 domain impact influenza virus polymerase function and replicationCharacteristics of nucleocytoplasmic transport of H1N1 influenza A virus nuclear export protein.Influenza A virus acquires enhanced pathogenicity and transmissibility after serial passages in swineInteractome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication.Targeting Importin-α7 as a Therapeutic Approach against Pandemic Influenza Viruses.Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human CellsThe ecology and adaptive evolution of influenza A interspecies transmissionCombination of PB2 271A and SR polymorphism at positions 590/591 is critical for viral replication and virulence of swine influenza virus in cultured cells and in vivoAn influenza reassortant with polymerase of pH1N1 and NS gene of H3N2 influenza A virus is attenuated in vivo.Restored PB1-F2 in the 2009 pandemic H1N1 influenza virus has minimal effects in swine.Influenza viruses with rearranged genomes as live-attenuated vaccines.Reassortment of NS segments modifies highly pathogenic avian influenza virus interaction with avian hosts and host cells.Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrierInfluenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIVRecruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicingPrimary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansionThe nuclear export protein of H5N1 influenza A viruses recruits Matrix 1 (M1) protein to the viral ribonucleoprotein to mediate nuclear export.Influenza A virus-generated small RNAs regulate the switch from transcription to replication.Engineered RNA viral synthesis of microRNAsA big role for small RNAs in influenza virus replicationInfluenza virus ribonucleoprotein complexes gain preferential access to cellular export machinery through chromatin targeting.Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.Architecture and regulation of negative-strand viral enzymatic machineryStructure-based design of NS2 mutants for attenuated influenza A virus vaccinesHighly pathogenic H5N1 influenza A virus strains provoke heterogeneous IFN-α/β responses that distinctively affect viral propagation in human cells.Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNAThe K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication.Systems to establish bunyavirus genome replication in the absence of transcription.Molecular signature of high yield (growth) influenza a virus reassortants prepared as candidate vaccine seeds.
P2860
Q21089600-F4BD332E-1102-49CE-892E-92305948CE67Q26852688-0B949C53-9CFC-4B16-8B5D-E38FA98CD1E8Q28115759-391996A2-88D3-462B-991C-EC440D615185Q28305057-69566604-ED71-49B9-B27C-8CCBB20780A9Q28483298-78762C4B-1462-41F3-B393-A8E0CCB18451Q30275435-E2E6A533-3C95-404B-9E81-90F825086964Q30354239-774FC500-E063-49E9-9A47-2A6DEBFCC1A5Q30360137-D6DB3D9B-2F1E-4B1D-ACA4-E2AB461935F4Q30361462-9A1499C9-4C7F-4D2D-8686-4A3D5BEAF936Q30365481-3DE68230-65A8-4DDD-8B57-4EA9637152D3Q30366402-DA0F64F1-9B2A-44C3-ADC4-78C3AEDAE5D2Q30375788-E9CD72F7-4333-4562-B590-6A7F62451EE3Q30386859-6EE5A993-ACCE-4300-A6F9-9A1E2C8ED301Q30390642-EB1278CB-2387-4E5C-8215-A69140F6142BQ30409242-696C8FE4-733D-4EAE-8201-E330977AC823Q30412888-7E73038C-4219-4452-94B8-190F97486039Q30413680-1F65CF44-0BAD-46A6-8A33-5519BF23B701Q30427712-7F4630A7-E893-4C67-A34D-6757715E40F3Q30427954-602A86C0-4181-455B-88C2-3C054A48595CQ30429748-5AB4B7A8-1276-4F8E-9D01-49D969621C5FQ30791826-79BCD82B-F7BD-4D77-875F-44BE13678530Q33614553-B5AE3466-A143-47B8-856B-D1BBD3613F9EQ33748942-B1027669-7800-4F56-AE48-A0A22B5C5D82Q33882912-4DDDD9DD-BB81-4BC9-AD9E-DE7A61639248Q33931158-64BAF8B9-72B3-424A-A416-CE4F70047799Q33953132-9871278E-1327-4846-B184-A3E9EB79A393Q33953313-4157B031-1BA7-4812-8BBA-4DC3E78BD848Q33953372-F566EC40-A656-4026-B68F-E4BCE28B8134Q34016192-67E78474-2327-48AC-9529-E6FE98C93FE1Q34022729-CA990279-C940-4FE1-80AF-2F8950737528Q34055461-5C676B91-387C-49BA-968D-FE5D32B5342AQ34055501-61AE6A14-9071-429B-9FEC-2BA8F3CF0DBFQ34171421-E3175B1B-BA8C-4B53-9698-0C57522B38FAQ34286309-9CF88922-8C33-4FE5-91F5-A8A31E6D63A2Q34441568-D0A88899-47F8-41A2-8232-63CB30FF0B53Q34602475-5CFF632D-C2E2-4E99-9277-78759F3DA402Q34629197-BB900230-4077-4A27-9023-925E312F0CE7Q34677745-27B9DFA6-14F8-4C41-930E-EDFFAAB71907Q34734608-525F246E-4D54-4E0B-A2AC-6434DEFC58D7Q34776101-CE4E7293-E254-472B-9F82-CE26D64F6B4B
P2860
NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@en
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@nl
type
label
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@en
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@nl
prefLabel
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@en
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@nl
P356
P1476
NS2/NEP protein regulates tran ...... he influenza virus RNA genome.
@en
P2093
Matt Smith
Nicole C Robb
P304
P356
10.1099/VIR.0.009639-0
P407
P577
2009-03-04T00:00:00Z