CD8(+) T-cell responses to adeno-associated virus capsid in humans.
about
Clinical development of gene therapy: results and lessons from recent successesTargeting adeno-associated virus and adenoviral gene therapy for hepatocellular carcinomaDevelopments in the treatment of hemophilia B: focus on emerging gene therapyThe gene therapy journey for hemophilia: are we there yet?Animal models of hemophiliaGene therapy for hemophiliaProgress and prospects: immune responses to viral vectorsSafety and efficacy of subretinal readministration of a viral vector in large animals to treat congenital blindnessInflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMDGene Therapy for Metabolic DiseasesGene therapy for rare diseases: summary of a National Institutes of Health workshop, September 13, 2012Microutrophin delivery through rAAV6 increases lifespan and improves muscle function in dystrophic dystrophin/utrophin-deficient miceRescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skippingWhole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapyTranslational data from adeno-associated virus-mediated gene therapy of hemophilia B in dogsDesigner gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transferDNA shuffling of adeno-associated virus yields functionally diverse viral progenyEvaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine modelsAAV's anatomy: roadmap for optimizing vectors for translational successAdenoviral Vectors for Hemophilia Gene TherapyHost and vector-dependent effects on the risk of germline transmission of AAV vectors.A preclinical animal model to assess the effect of pre-existing immunity on AAV-mediated gene transfer.Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaquesImmune responses to AAV in canine muscle monitored by cellular assays and noninvasive imaging.Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice.Hepatic gene transfer as a means of tolerance induction to transgene productsAnti-inflammatory loaded poly-lactic glycolic acid nanoparticle formulations to enhance myocardial gene transfer: an in-vitro assessment of a drug/gene combination therapeutic approach for direct injection.Bioengineered factor IX molecules with increased catalytic activity improve the therapeutic index of gene therapy vectors for hemophilia BAAV provides an alternative for gene therapy of the peripheral sensory nervous system.Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primatesGene and cell-mediated therapies for muscular dystrophy.Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.The potential of adeno-associated viral vectors for gene delivery to muscle tissue.Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions.Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors.Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.Gene therapy with mitochondrial heat shock protein 70 suppresses visual loss and optic atrophy in experimental autoimmune encephalomyelitis.
P2860
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P2860
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
@en
type
label
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
@en
prefLabel
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
@en
P2093
P50
P356
P1433
P1476
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
@en
P2093
Daniel J Hui
Denise E Sabatino
Federico Mingozzi
Glenn F Pierce
Hildegund C J Ertl
John E J Rasko
Jurg Sommer
Katherine A High
Margaret V Ragni
Samuel L Murphy
P2888
P304
P356
10.1038/NM1549
P407
P577
2007-03-18T00:00:00Z
P6179
1011727524