Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants.
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Adaptation to Human Populations Is Revealed by Within-Host Polymorphisms in HIV-1 and Hepatitis C VirusMutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to manEstimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.Vaccination and timing influence SIV immune escape viral dynamics in vivo.Dynamics of immune escape during HIV/SIV infection.The specificity and polymorphism of the MHC class I prevents the global adaptation of HIV-1 to the monomorphic proteasome and TAP.Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys.Reversion in vivo after inoculation of a molecular proviral DNA clone of simian immunodeficiency virus with a cytotoxic-T-lymphocyte escape mutationUse of molecular beacons for rapid, real-time, quantitative monitoring of cytotoxic T-lymphocyte epitope mutations in simian immunodeficiency virusSexual transmission of single human immunodeficiency virus type 1 virions encoding highly polymorphic multisite cytotoxic T-lymphocyte escape variants.Sequence evolution of HIV-1 following mother-to-child transmission.Involvement of multiple epitope-specific cytotoxic T-lymphocyte responses in vaccine-based control of simian immunodeficiency virus replication in rhesus macaques.Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral controlFitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1The Effect of Interference on the CD8(+) T Cell Escape Rates in HIV.Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection.Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses.Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation.In vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaquesUnderstanding the failure of CD8+ T-cell vaccination against simian/human immunodeficiency virus.Investigating the Consequences of Interference between Multiple CD8+ T Cell Escape Mutations in Early HIV Infection.Live attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239.Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.Effects of MIP-1 alpha, MIP-3 alpha, and MIP-3 beta on the induction of HIV Gag-specific immune response with DNA vaccines.Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitopeEnhancing efficacy of HIV gag DNA vaccine by local delivery of GM-CSF in murine and macaque models.HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus.Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infantDiverse cross-reactive potential and Vbeta gene usage of an epitope-specific cytotoxic T-lymphocyte population in monkeys immunized with diverse human immunodeficiency virus type 1 Env immunogens.Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys.Different abilities of escape mutant-specific cytotoxic T cells to suppress replication of escape mutant and wild-type human immunodeficiency virus type 1 in new hostsVaccine-induced T cells control reversion of AIDS virus immune escape mutantsAntiviral T cell responses: phalanx or multipronged attack?Complex assembly, crystallization and preliminary X-ray crystallographic studies of rhesus macaque MHC Mamu-A*01 complexed with an immunodominant SIV-Gag nonapeptide.
P2860
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P2860
Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Dynamic immune responses maint ...... munodeficiency virus variants.
@en
Dynamic immune responses maint ...... munodeficiency virus variants.
@nl
type
label
Dynamic immune responses maint ...... munodeficiency virus variants.
@en
Dynamic immune responses maint ...... munodeficiency virus variants.
@nl
prefLabel
Dynamic immune responses maint ...... munodeficiency virus variants.
@en
Dynamic immune responses maint ...... munodeficiency virus variants.
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Dynamic immune responses maint ...... munodeficiency virus variants.
@en
P2093
Angela Carville
Carol I Lord
Dan H Barouch
Darci A Gorgone
Diana M Truitt
Fred W Peyerl
Jennifer Powers
Keith G Mansfield
Kevin J Kunstman
Marcelo J Kuroda
P2860
P304
P356
10.1038/NI1167
P407
P577
2005-01-30T00:00:00Z