Differential signaling pathways are activated in the Epstein-Barr virus-associated malignancies nasopharyngeal carcinoma and Hodgkin lymphoma.
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Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73αEBV latent membrane protein 1 activates Akt, NFkappaB, and Stat3 in B cell lymphomas.Epstein-Barr virus associated modulation of Wnt pathway is not dependent on latent membrane protein-1.Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency.Epigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinomaAlterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in radioresistant nasopharyngeal carcinoma cellsE-cadherin and beta-catenin expression in Epstein-Barr virus-associated gastric carcinoma and their prognostic significanceEpstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasis.Long non-coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival.HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3.RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosisEpstein-Barr virus BALF3 mediates genomic instability and progressive malignancy in nasopharyngeal carcinoma.Expression profiling of 21 biomolecules in locally advanced nasopharyngeal carcinomas of Caucasian patients.Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis.Inhibition of GSK 3β activity is associated with excessive EZH2 expression and enhanced tumour invasion in nasopharyngeal carcinoma.Molecular markers to assess short-term disease local recurrence in nasopharyngeal carcinoma.The cadherin-catenin complex in nasopharyngeal carcinomaPuquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cellsEpstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway.Unusual coexistence of extramedullary plasmacytoma and nasopharyngeal carcinoma in nasopharynxGenetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy.Transcriptome changes induced by Epstein-Barr virus LMP1 and LMP2A in transgenic lymphocytes and lymphoma.Notch and Wnt signaling: mimicry and manipulation by gamma herpesviruses.Novel small-molecule therapy of Hodgkin lymphoma.Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cells.EBV latent membrane protein 1 effects on plakoglobin, cell growth, and migration.Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch.Accumulation of cytoplasmic beta-catenin and nuclear glycogen synthase kinase 3beta in Epstein-Barr virus-infected cells.GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.Glycogen synthase kinase 3 beta: can it be a target for oral cancer.Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma.Beyond chemotherapy: new agents for targeted treatment of lymphomaMulticenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079).Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC.The emerging role of GSK-3β in the pathobiology of classical Hodgkin lymphoma.IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling.Upregulation of Caveolin-1 correlate with Akt expression and poor prognosis in NPC patients.Preclinical evaluation of the PI3K-mTOR dual inhibitor PF-04691502 as a novel therapeutic drug in nasopharyngeal carcinoma.Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.
P2860
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P2860
Differential signaling pathways are activated in the Epstein-Barr virus-associated malignancies nasopharyngeal carcinoma and Hodgkin lymphoma.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@en
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@nl
type
label
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@en
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@nl
prefLabel
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@en
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@nl
P2093
P1433
P1476
Differential signaling pathway ...... arcinoma and Hodgkin lymphoma.
@en
P2093
Jennifer A Morrison
Margaret L Gulley
Nancy Raab-Traub
Rajadurai Pathmanathan
P304
P356
10.1158/0008-5472.CAN-04-0538
P407
P577
2004-08-01T00:00:00Z