High-throughput gene expression profiling indicates dysregulation of intestinal cell cycle mediators and growth factors during primary simian immunodeficiency virus infection.
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The simian immunodeficiency virus targets central cell cycle functions through transcriptional repression in vivoTranscriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalizationmiR-190b is markedly upregulated in the intestine in response to simian immunodeficiency virus replication and partly regulates myotubularin-related protein-6 expressionMicropatterned co-cultures of T-lymphocytes and epithelial cells as a model of mucosal immune systemPersistence of gut mucosal innate immune defenses by enteric α-defensin expression in the simian immunodeficiency virus model of AIDS.Progressive proximal-to-distal reduction in expression of the tight junction complex in colonic epithelium of virally-suppressed HIV+ individuals.Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regenerationGut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors.Intestinal epithelial barrier disruption through altered mucosal microRNA expression in human immunodeficiency virus and simian immunodeficiency virus infectionsSimian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.Isolation and characterization of intestinal epithelial cells from normal and SIV-infected rhesus macaquesFocused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction.Improvement of intestinal permeability with alanyl-glutamine in HIV patients: a randomized, double blinded, placebo-controlled clinical trial.Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge.Enhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection.Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques.Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infectionTranscription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection.High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations.Gut epithelial barrier and systemic inflammation during chronic HIV infection.Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques.The role of disease stage, plasma viral load and regulatory T cells (Tregs) on autoantibody production in SIV-infected non-human primatesInsights into host responses against pathogens from transcriptional profiling.Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration.Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cellsFoamy virus infection in primates.Microbial translocation in the pathogenesis of HIV infection and AIDS.HIV-associated mucosal gene expression: region-specific alterationsSuppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection.Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection.Old world monkeys and new age science: the evolution of nonhuman primate systems virology.Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats.Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys.Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response.Gastric transcription profile of Helicobacter pylori infection in the rhesus macaqueIdentification of molecular sub-networks associated with cell survival in a chronically SIVmac-infected human CD4+ T cell line.Express path analysis identifies a tyrosine kinase Src-centric network regulating divergent host responses to Mycobacterium tuberculosis infectionThe effect of timing of antiretroviral therapy on CD4+ T-cell reconstitution in the intestine of HIV-infected patients.The role of polymorphonuclear neutrophils during HIV-1 infection.Simian immunodeficiency virus infection induces severe loss of intestinal central memory T cells which impairs CD4+ T-cell restoration during antiretroviral therapy.
P2860
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P2860
High-throughput gene expression profiling indicates dysregulation of intestinal cell cycle mediators and growth factors during primary simian immunodeficiency virus infection.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
High-throughput gene expressio ...... unodeficiency virus infection.
@en
High-throughput gene expressio ...... unodeficiency virus infection.
@nl
type
label
High-throughput gene expressio ...... unodeficiency virus infection.
@en
High-throughput gene expressio ...... unodeficiency virus infection.
@nl
prefLabel
High-throughput gene expressio ...... unodeficiency virus infection.
@en
High-throughput gene expressio ...... unodeficiency virus infection.
@nl
P2093
P1433
P1476
High-throughput gene expressio ...... unodeficiency virus infection.
@en
P2093
Angie C Gelli
Elizabeth Reay
Michael D George
Satya Dandekar
Sumathi Sankaran
P356
10.1016/S0042-6822(03)00207-1
P407
P577
2003-07-01T00:00:00Z