Human T-cell lymphotropic virus type 1 tax inhibits transforming growth factor-beta signaling by blocking the association of Smad proteins with Smad-binding element.
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The HTLV-1 Tax interactomeHuman T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)The Role of HBZ in HTLV-1-Induced OncogenesisModes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and PersistenceTGF-β - an excellent servant but a bad masterSevere acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signalingTax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat.Molecular mechanisms of cellular transformation by HTLV-1 Tax.Common critical pathways in embryogenesis and cancer.Distinct expression profiles of TGF-beta1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections.HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.Two major Smad pathways in TGF-beta superfamily signalling.HTLV-1 bZIP factor enhances TGF-β signaling through p300 coactivator.Human papillomavirus type 5 E6 oncoprotein represses the transforming growth factor beta signaling pathway by binding to SMAD3Human T-cell leukemia virus type I and adult T-cell leukemia.Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades.Transforming growth factor-beta signaling in normal and malignant hematopoiesis.Kaposi's sarcoma-associated herpesvirus-encoded microRNA miR-K12-11 attenuates transforming growth factor beta signaling through suppression of SMAD5.Transforming growth factor beta1 receptor II is downregulated by E1A in adenovirus-infected cellsPersistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.Deregulated TGF-beta signaling in leukemogenesis.Deregulation of cell-signaling pathways in HTLV-1 infection.Role of transforming growth factor-beta in hematologic malignanciesKSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor.Dysregulation of TGF-beta signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease.How HTLV-1 may subvert miRNAs for persistence and transformation.Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication.The role of Smad signaling in hematopoiesis and translational hematology.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.Molecular hallmarks of adult T cell leukemia.Development of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma.Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules.A Kaposi's sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor β pathway to promote cell survival.Modulation of T cell responses in HTLV-1 carriers and in patients with myelopathy associated with HTLV-1.HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors.Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice.Tumour promoting functions of TGF-β in CML-initiating cells.Inactivation of hTERT transcription by Tax.Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer.
P2860
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P2860
Human T-cell lymphotropic virus type 1 tax inhibits transforming growth factor-beta signaling by blocking the association of Smad proteins with Smad-binding element.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@en
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@nl
type
label
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@en
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@nl
prefLabel
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@en
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@nl
P2093
P2860
P356
P1476
Human T-cell lymphotropic viru ...... ins with Smad-binding element.
@en
P2093
Byung-Chul Kim
Dug Keun Lee
John N Brady
Kuan-Teh Jeang
Seong-Jin Kim
P2860
P304
33766-33775
P356
10.1074/JBC.M200150200
P407
P577
2002-07-03T00:00:00Z