Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer.
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TonB induces conformational changes in surface-exposed loops of FhuA, outer membrane receptor of Escherichia coli.HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants.Antigenic and 3D structural characterization of soluble X4 and hybrid X4-R5 HIV-1 Env trimersSoluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state.Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigsEvaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformationVirus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain.Oligomeric structure of the human immunodeficiency virus type 1 envelope protein on the virion surface.Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.Increased functional stability and homogeneity of viral envelope spikes through directed evolution.Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3- and a trimer-specific gp41 antibody.HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies.Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer.Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding siteStability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor bindingHIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine DesignPromoting trimerization of soluble human immunodeficiency virus type 1 (HIV-1) Env through the use of HIV-1/simian immunodeficiency virus chimeras.Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d.Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein.Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein.Heterologous protein production using euchromatin-containing expression vectors in mammalian cellsFunctional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41.Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein.Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1.Subunit stoichiometry of human immunodeficiency virus type 1 envelope glycoprotein trimers during virus entry into host cells.Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.Design, expression, and immunogenicity of a soluble HIV trimeric envelope fragment adopting a prefusion gp41 configuration.The SCHOOL of nature: IV. Learning from viruses.Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle.Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.Comparison of Uncleaved and Mature Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimers.
P2860
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P2860
Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Expression, purification, and ...... lope glycoprotein as a trimer.
@en
Expression, purification, and ...... lope glycoprotein as a trimer.
@nl
type
label
Expression, purification, and ...... lope glycoprotein as a trimer.
@en
Expression, purification, and ...... lope glycoprotein as a trimer.
@nl
prefLabel
Expression, purification, and ...... lope glycoprotein as a trimer.
@en
Expression, purification, and ...... lope glycoprotein as a trimer.
@nl
P2093
P2860
P356
P1476
Expression, purification, and ...... lope glycoprotein as a trimer.
@en
P2093
P2860
P304
39577-39585
P356
10.1074/JBC.M107147200
P407
P577
2001-08-20T00:00:00Z