Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation.
about
Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-PolRequirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.A single amino acid substitution in HIV-1 reverse transcriptase significantly reduces virion release.Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex.The foamy virus genome remains unintegrated in the nuclei of G1/S phase-arrested cells, and integrase is critical for preintegration complex transport into the nucleus.Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core.Individual contributions of mutant protease and reverse transcriptase to viral infectivity, replication, and protein maturation of antiretroviral drug-resistant human immunodeficiency virus type 1.Moloney murine leukemia virus integrase protein augments viral DNA synthesis in infected cells.Analysis of human immunodeficiency virus type 1 reverse transcriptase subunit structure/function in the context of infectious virions and human target cells.Virion instability of human immunodeficiency virus type 1 reverse transcriptase (RT) mutated in the protease cleavage site between RT p51 and the RT RNase H domain.Placement of leucine zipper motifs at the carboxyl terminus of HIV-1 protease significantly reduces virion production.Impairment of human immunodeficiency virus type-1 integrase SUMOylation correlates with an early replication defect.Gag-Pol Transframe Domain p6* Is Essential for HIV-1 Protease-Mediated Virus Maturation.pol gene diversity of five human immunodeficiency virus type 1 subtypes: evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D.Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription.Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication.Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): naturally selected mutations in IN augment DNA synthesis.The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA.Identifying and characterizing a functional HIV-1 reverse transcriptase-binding site on integrase.Integrase interacts with nucleoporin NUP153 to mediate the nuclear import of human immunodeficiency virus type 1Uncoupling human immunodeficiency virus type 1 Gag and Pol reading frames: role of the transframe protein p6* in viral replication.Targeting human immunodeficiency virus type 1 assembly, maturation and budding.C-Terminal HIV-1 Transframe p6* Tetrapeptide Blocks Enhanced Gag Cleavage Incurred by Leucine Zipper Replacement of a Deleted p6* Domain.Mutations in the primer grip of human immunodeficiency virus type 1 reverse transcriptase impair proviral DNA synthesis and virion maturation.The dimer interfaces of protease and extra-protease domains influence the activation of protease and the specificity of GagPol cleavage.Human immunodeficiency virus type 1 (HIV-1) protein Vif inhibits the activity of HIV-1 protease in bacteria and in vitro.Initial cleavage of the human immunodeficiency virus type 1 GagPol precursor by its activated protease occurs by an intramolecular mechanism.Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus.Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase.Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical human immunodeficiency virus type 1 isolate with a deletion of codon 69 in the reverse transcriptase coding region.Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors.Dynamics of HIV replication in lymphocytes and the efficacy of protease inhibitors.Suppression of HIV replication using RNA interference against HIV-1 integrase.HIV-1 protease with leucine zipper fused at N-terminus exhibits enhanced linker amino acid-dependent activity.
P2860
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P2860
Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Extensive regions of pol are r ...... ssing and particle maturation.
@en
Extensive regions of pol are r ...... ssing and particle maturation.
@nl
type
label
Extensive regions of pol are r ...... ssing and particle maturation.
@en
Extensive regions of pol are r ...... ssing and particle maturation.
@nl
prefLabel
Extensive regions of pol are r ...... ssing and particle maturation.
@en
Extensive regions of pol are r ...... ssing and particle maturation.
@nl
P2093
P356
P1433
P1476
Extensive regions of pol are r ...... essing and particle maturation
@en
P2093
P356
10.1006/VIRO.1996.0219
P407
P50
P577
1996-05-01T00:00:00Z