Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.
about
Rates of spontaneous mutationA human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphateAssessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutationsAbsence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected miceAntimutator variants of DNA polymerasesInhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complexEffects of exonuclease activity and nucleotide selectivity of the herpes simplex virus DNA polymerase on the fidelity of DNA replication in vivo.Identification and characterization of a novel herpes simplex virus glycoprotein, gK, involved in cell fusionMutator suppression and escape from replication error-induced extinction in yeastHigh-frequency phenotypic reversion and pathogenicity of an acyclovir-resistant herpes simplex virus mutant.The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerasesHerpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycinIncorporation of 1-beta-D-arabinofuranosylcytosine into DNA and mutagenesis of herpes simplex virus type 1.Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteinsHerpes simplex virus immediate-early proteins ICP0 and ICP4 activate the endogenous human alpha-globin gene in nonerythroid cells.Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity.Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients.Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site.Mutations in accessory DNA replicating functions alter the relative mutation frequency of herpes simplex virus type 1 strains in cultured murine cells.Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhsGenetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.Use of suppressor analysis to identify DNA polymerase mutations in herpes simplex virus which affect deoxynucleoside triphosphate substrate specificity.Sequence requirements for DNA rearrangements induced by the terminal repeat of herpes simplex virus type 1 KOS DNACharacterization of a major DNA-binding domain in the herpes simplex virus type 1 DNA-binding protein (ICP8).Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant.Regulation of cellular genes transduced by herpes simplex virus.Regulation of herpes simplex virus true late gene expression: sequences downstream from the US11 TATA box inhibit expression from an unreplicated templateAphidicolin resistance in herpes simplex virus type 1 appears to alter substrate specificity in the DNA polymeraseExamination of the roles of transcription factor Sp1-binding sites and an octamer motif in trans induction of the herpes simplex virus thymidine kinase gene.Direct method for quantitation of extreme polymerase error frequencies at selected single base sites in viral RNA.Measurement of the mutation rates of animal viruses: influenza A virus and poliovirus type 1.Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locusExpression of a cellular gene cloned in herpes simplex virus: rabbit beta-globin is regulated as an early viral gene in infected fibroblasts.Herpes simplex virus type 2 mutagenesis: characterization of mutants induced at the hprt locus of nonpermissive XC cellsFinger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.Frequency of acyclovir-resistant herpes simplex virus in clinical specimens and laboratory isolates.
P2860
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P2860
Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh-hant
name
Generation of genetic diversit ...... s to the DNA polymerase locus.
@en
Generation of genetic diversit ...... s to the DNA polymerase locus.
@nl
type
label
Generation of genetic diversit ...... s to the DNA polymerase locus.
@en
Generation of genetic diversit ...... s to the DNA polymerase locus.
@nl
prefLabel
Generation of genetic diversit ...... s to the DNA polymerase locus.
@en
Generation of genetic diversit ...... s to the DNA polymerase locus.
@nl
P2093
P1433
P1476
Generation of genetic diversit ...... s to the DNA polymerase locus.
@en
P2093
Schaffer PA
Weisslitz M
P356
10.1016/0042-6822(84)90088-6
P407
P577
1984-01-01T00:00:00Z