Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells. - Wikidata - awgldk - TriplyDB

Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells.

Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells.

http://www.wikidata.org/entity/Q45867392

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Progresses towards safe and efficient gene therapy vectors Hematopoietic stem cell engineering at a crossroads Gene therapy studies in a canine model of X-linked severe combined immunodeficiency Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates.Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model.Concise review: lessons learned from clinical trials of gene therapy in monogenic immunodeficiency diseases.Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis.Neonatal intravenous injection of a gammaretroviral vector has a low incidence of tumor induction in mice.Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.Large animal models of hematopoietic stem cell gene therapy.Regulated apoptosis of genetically modified hematopoietic stem and progenitor cells via an inducible caspase-9 suicide gene in rhesus macaques.Lentiviral vector integration profiles differ in rodent postmitotic tissues Long-term regulation of genetically modified primary hematopoietic cells in dogs.Lentiviral gene transfer into the dorsal root ganglion of adult rats.Retroviral integration site selection.Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies.VISA--Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing.Insights into leukemia-initiating cell frequency and self-renewal from a novel canine model of leukemia.Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selection Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors.Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity.Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model.Lentivirus-mediated platelet gene therapy of murine hemophilia A with pre-existing anti-factor VIII immunity.A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors.A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells.Genotypic features of lentivirus transgenic mice.CD34(+) expansion with Delta-1 and HOXB4 promotes rapid engraftment and transfusion independence in a Macaca nemestrina cord blood transplant model A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance.Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients Generation of transgenic marmosets expressing genetically encoded calcium indicators.Identification of Hematopoietic Stem Cell Engraftment Genes in Gene Therapy Studies.Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency.No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids.Genotoxicity of retroviral hematopoietic stem cell gene therapy.

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P2860

Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells.

http://www.wikidata.org/entity/Q45867392

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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name

Comparison of HIV-derived lent ...... in primate repopulating cells.

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Comparison of HIV-derived lent ...... in primate repopulating cells.

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type

label

Comparison of HIV-derived lent ...... in primate repopulating cells.

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Comparison of HIV-derived lent ...... in primate repopulating cells.

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Comparison of HIV-derived lent ...... in primate repopulating cells.

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Comparison of HIV-derived lent ...... in primate repopulating cells.

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Molecular Therapy

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Brian C Beard

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Christina Gooch

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David Dickerson

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Grant D Trobridge

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Hans-Peter Kiem

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James Fletcher

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Michael A Jacobs

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Rajinder Kaul

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Tulin Okbinoglu

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1356-1365

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scholarly article

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10.1038/SJ.MT.6300159

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7

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15

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Daniel G. Miller

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2007-04-17T00:00:00Z

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6389053

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17440443

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