Inhibitory effect of ketoconazole on the pharmacokinetics of a multireceptor tyrosine kinase inhibitor BMS-690514 in healthy participants: assessing the mechanism of the interaction with physiologically-based pharmacokinetic simulations.
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Ketoconazole-Associated Liver Injury in Drug-Drug Interaction Studies in Healthy Volunteers.Effects of Ketoconazole on the Pharmacokinetics of Lenvatinib (E7080) in Healthy ParticipantsDirect inhibition of Re Du Ning Injection and its active compounds on human liver cytochrome P450 enzymes by a cocktail method.Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats.Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies.The Application of Physiologically Based Pharmacokinetic Modeling to Predict the Role of Drug Transporters: Scientific and Regulatory Perspectives.PBPK model describes the effects of comedication and genetic polymorphism on systemic exposure of drugs that undergo multiple clearance pathways.Evaluation of the likelihood of a selective CHK1 inhibitor (LY2603618) to inhibit CYP2D6 with desipramine as a probe substrate in cancer patients.
P2860
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P2860
Inhibitory effect of ketoconazole on the pharmacokinetics of a multireceptor tyrosine kinase inhibitor BMS-690514 in healthy participants: assessing the mechanism of the interaction with physiologically-based pharmacokinetic simulations.
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2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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name
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@en
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@nl
type
label
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@en
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@nl
prefLabel
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@en
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@nl
P2093
P2860
P356
P1476
Inhibitory effect of ketoconaz ...... d pharmacokinetic simulations.
@en
P2093
Blisse Vakkalagadda
Christoph M Ahlers
Eric Masson
Guoxiang Shen
John F Kurland
Lisa J Christopher
Steven Zhang
Teresa Has
Vikram Roongta
Zheng Yang
P2860
P304
P356
10.1177/0091270012439208
P577
2013-02-01T00:00:00Z