Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities.
about
The tertiary structure and domain organization of coagulation factor VIIIStructure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopesStorage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cellsThe 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfacesIdentification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites.Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies.Membrane-binding properties of the Factor VIII C2 domain.Mild/moderate haemophilia A: new insights into molecular mechanisms and inhibitor development.Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen-deuterium exchange mass spectrometry.In silico analyses of missense mutations in coagulation factor VIII: identification of severity determinants of haemophilia A.Characterization of five associations of F8 missense mutations containing FVIII B domain mutations.
P2860
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P2860
Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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2004年學術文章
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2004年學術文章
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name
Surface-exposed hemophilic mut ...... bility and binding activities.
@en
Surface-exposed hemophilic mut ...... bility and binding activities.
@nl
type
label
Surface-exposed hemophilic mut ...... bility and binding activities.
@en
Surface-exposed hemophilic mut ...... bility and binding activities.
@nl
prefLabel
Surface-exposed hemophilic mut ...... bility and binding activities.
@en
Surface-exposed hemophilic mut ...... bility and binding activities.
@nl
P2093
P2860
P356
P1476
Surface-exposed hemophilic mut ...... bility and binding activities.
@en
P2093
Barry L Stoddard
P Clint Spiegel
Paul Murphy
P2860
P304
53691-53698
P356
10.1074/JBC.M409389200
P407
P577
2004-10-07T00:00:00Z