Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). - Wikidata - awgldk - TriplyDB

Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I).

Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I).

http://www.wikidata.org/entity/Q45882616

about

Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]Extracellular matrix production in vitro in cartilage tissue engineering The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta.Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer Orthopedic gene therapy in 2008.Signaling pathways in cartilage repair.Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate.Strategies for osteochondral repair: Focus on scaffolds.Clinical potential and challenges of using genetically modified cells for articular cartilage repair.Sonic hedgehog improves redifferentiation of dedifferentiated chondrocytes for articular cartilage repair.Release of bioactive adeno-associated virus from fibrin scaffolds: effects of fibrin glue concentrations.Effects of phosphorylatable short peptide-conjugated chitosan-mediated IL-1Ra and igf-1 gene transfer on articular cartilage defects in rabbits.Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid.Chondroprotective effects of a proanthocyanidin rich Amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1 production by human chondrocytes.Major biological obstacles for persistent cell-based regeneration of articular cartilage.Gene delivery strategies for cartilage tissue engineering New findings in osteoarthritis pathogenesis: therapeutic implications.Gene transfer strategies in tissue engineering Harnessing cell–biomaterial interactions for osteochondral tissue regeneration.Gene therapy for articular cartilage repair.Engineering cartilage tissue Concepts in gene therapy for cartilage repair.Role of sox9 in growth factor regulation of articular chondrocytes.Interleukin-1 beta and tumor necrosis factor alpha inhibit migration activity of chondrogenic progenitor cells from non-fibrillated osteoarthritic cartilage Growth factor transgenes interactively regulate articular chondrocytes.Controlled delivery systems: from pharmaceuticals to cells and genes.Rehabilitation and return-to-sports activity after debridement and bone marrow stimulation of osteochondral talar defects.Tissue-engineering strategies to repair joint tissue in osteoarthritis: nonviral gene-transfer approaches.Tissue-engineered cartilage: the crossroads of biomaterials, cells and stimulating factors.Gene Therapy for Cartilage Repair.Effects of solid acellular type-I/III collagen biomaterials on in vitro and in vivo chondrogenesis of mesenchymal stem cells.Growth factor regulation of growth factor production by multiple gene transfer to chondrocytes.Advanced Strategies for Articular Cartilage Defect Repair.BMP-2 gene activated muscle tissue fragments for osteochondral defect regeneration in the rabbit knee.Delivering Nucleic-Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives.Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair Cell-laden hydrogels for osteochondral and cartilage tissue engineering.Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis.Silencing of anti-chondrogenic microRNA-221 in human mesenchymal stem cells promotes cartilage repair in vivo.Combination of baculovirus-expressed BMP-2 and rotating-shaft bioreactor culture synergistically enhances cartilage formation.

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Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I).

http://www.wikidata.org/entity/Q45882616

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P2860

Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation

Marrow stromal cells embedded in alginate for repair of osteochondral defects.

Transforming growth factor-beta in calcium alginate beads for the treatment of articular cartilage defects in the rabbit.

Dedifferentiated chondrocytes cultured in alginate beads: restoration of the differentiated phenotype and of the metabolic responses to interleukin-1beta.

Preparation of regular sized Ca-alginate microspheres using membrane emulsification method.

Insulin-like growth factor-I enhances cell-based repair of articular cartilage.

Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system.

Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells.

Efficient lipid-mediated gene transfer to articular chondrocytes.

Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation.

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