A single gene determines the host range of influenza virus.
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Pandemic Threat Posed by Avian Influenza A VirusesEmergence of influenza A virusesEvolution and ecology of influenza A virusesOne health, multiple challenges: The inter-species transmission of influenza A virusAvian influenza A viruses: from zoonosis to pandemicInfluenza A virus polymerase is a site for adaptive changes during experimental evolution in bat cellsAnalysis by single-gene reassortment demonstrates that the 1918 influenza virus is functionally compatible with a low-pathogenicity avian influenza virus in mice.Conserved features of the PB2 627 domain impact influenza virus polymerase function and replicationContemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin.An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase.Full factorial analysis of mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptationInterspecies transmission and host restriction of avian H5N1 influenza virus.Evolution of the M gene of the influenza A virus in different host species: large-scale sequence analysis.PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells.Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human CellsThe PB2-E627K mutation attenuates viruses containing the 2009 H1N1 influenza pandemic polymeraseA new concept of the epidemic process of influenza A virusReassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriersReplication of avian influenza A viruses in mammals.Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and pH of fusion: implications for host range and adaptationMolecular and serological investigations of the Influenza A(H1N1) 2009 pandemic virus in Turkey.Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrierThe host-dependent interaction of alpha-importins with influenza PB2 polymerase subunit is required for virus RNA replication.Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways.Rapid evolution of H5N1 influenza viruses in chickens in Hong Kong.The role of influenza A virus hemagglutinin residues 226 and 228 in receptor specificity and host range restriction.Molecular correlates of influenza A H5N1 virus pathogenesis in mice.The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.Hemagglutinin mutants of swine influenza virus differing in replication characteristics in their natural host.Unusual influenza A viruses in bats.Role of receptor binding specificity in influenza A virus transmission and pathogenesis.Enhanced neurovirulence of borna disease virus variants associated with nucleotide changes in the glycoprotein and L polymerase genes.The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit.Quantifying the fitness advantage of polymerase substitutions in Influenza A/H7N9 viruses during adaptation to humans.Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes.NS1 proteins of avian influenza A viruses can act as antagonists of the human alpha/beta interferon response.Cell receptors for influenza a viruses and the innate immune responseSpecies difference in ANP32A underlies influenza A virus polymerase host restrictionInvestigation of influenza virus polymerase activity in pig cells.Defective interfering influenza viruses and host cells: establishment and maintenance of persistent influenza virus infection in MDBK and HeLa cells.
P2860
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P2860
A single gene determines the host range of influenza virus.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年学术文章
@wuu
1977年学术文章
@zh
1977年学术文章
@zh-cn
1977年学术文章
@zh-hans
1977年学术文章
@zh-my
1977年学术文章
@zh-sg
1977年學術文章
@yue
1977年學術文章
@zh-hant
name
A single gene determines the host range of influenza virus.
@en
A single gene determines the host range of influenza virus.
@nl
type
label
A single gene determines the host range of influenza virus.
@en
A single gene determines the host range of influenza virus.
@nl
prefLabel
A single gene determines the host range of influenza virus.
@en
A single gene determines the host range of influenza virus.
@nl
P2860
P356
P1433
P1476
A single gene determines the host range of influenza virus.
@en
P2093
P2860
P2888
P304
P356
10.1038/270617A0
P407
P577
1977-12-01T00:00:00Z
P6179
1008990338