Pharmacodynamics of selective inhibition of γ-secretase by avagacestat. - Wikidata - awgldk - TriplyDB

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

http://www.wikidata.org/entity/Q45908140

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γ-Secretase inhibitors and modulators.Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.Impact of acamprosate on plasma amyloid-β precursor protein in youth: a pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker.Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β.Alzheimer's Disease: Lessons Learned from Amyloidocentric Clinical Trials.Advances in recent patent and clinical trial drug development for Alzheimer's disease.Future Therapeutics in Alzheimer's Disease: Development Status of BACE Inhibitors.Amyloid Hypothesis: Is There a Role for Antiamyloid Treatment in Late-Life Depression?Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects.New treatment strategies for Alzheimer's disease: is there a hope?Novel γ-secretase modulators for the treatment of Alzheimer's disease: a review focusing on patents from 2010 to 2012.Interpreting Alzheimer's disease clinical trials in light of the effects on amyloid-β.Rab21, a Novel PS1 Interactor, Regulates γ-Secretase Activity via PS1 Subcellular Distribution.Inhibition of γ-Secretase Leads to an Increase in Presenilin-1.Gamma secretase inhibitors: a patent review (2013 - 2015).γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.Pharmacological Agents Targeting γ-Secretase Increase Risk of Cancer and Cognitive Decline in Alzheimer's Disease Patients: A Systematic Review and Meta-Analysis.Amyloid beta modulators and neuroprotection in Alzheimer's disease: a critical appraisal.Perspectives on the discovery of NOTCH2-specific inhibitors.What lessons can be learned from failed Alzheimer's disease trials?Efficient production of a mature and functional gamma secretase protease

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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

http://www.wikidata.org/entity/Q45908140

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh-hant

name

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

@en

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

@nl

type

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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

@nl

prefLabel

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

@en

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

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JPET.112.199356

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Journal of Pharmacology and Experimental Therapeutics

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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat

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Catherine Burton

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Charles F Albright

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Craig Polson

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Donna M Barten

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Gary Pilcher

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Gary Tong

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Jere E Meredith

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Jeremy H Toyn

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Joanne Bronson

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John E Macor

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scholarly article

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