Flavones as colorectal cancer chemopreventive agents--phenol-o-methylation enhances efficacy.
about
Methylation of dietary flavones increases their metabolic stability and chemopreventive effectsGuidelines for the welfare and use of animals in cancer research.Preclinical colorectal cancer chemopreventive efficacy and p53-modulating activity of 3',4',5'-trimethoxyflavonol, a quercetin analogue.Apigenin and its impact on gastrointestinal cancers.A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.A Dihydroxy-pentamethoxyflavone from Gardenia obtusifolia suppresses proliferation and promotes apoptosis of tumor cells through modulation of multiple cell signaling pathways.Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-13',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathwayPretreatment serum xanthophyll concentrations as predictors of head and neck cancer recurrence and survival.Impact of apigenin and kaempferol on human head and neck squamous cell carcinoma.Biological evaluation and SAR analysis of O-methylated analogs of quercetin as inhibitors of cancer cell proliferation.Structure, bioactivity, and synthesis of methylated flavonoids.Tricin inhibits proliferation of human hepatic stellate cells in vitro by blocking tyrosine phosphorylation of PDGF receptor and its signaling pathways.Dietary intake of rosmarinic acid by Apc(Min) mice, a model of colorectal carcinogenesis: levels of parent agent in the target tissue and effect on adenoma development.Pharmacokinetics in mice and metabolism in murine and human liver fractions of the putative cancer chemopreventive agents 3',4',5',5,7-pentamethoxyflavone and tricin (4',5,7-trihydroxy-3',5'-dimethoxyflavone).Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action.
P2860
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P2860
Flavones as colorectal cancer chemopreventive agents--phenol-o-methylation enhances efficacy.
description
2009 nî lūn-bûn
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2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
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2009年學術文章
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name
Flavones as colorectal cancer ...... methylation enhances efficacy.
@en
Flavones as colorectal cancer ...... methylation enhances efficacy.
@nl
type
label
Flavones as colorectal cancer ...... methylation enhances efficacy.
@en
Flavones as colorectal cancer ...... methylation enhances efficacy.
@nl
prefLabel
Flavones as colorectal cancer ...... methylation enhances efficacy.
@en
Flavones as colorectal cancer ...... methylation enhances efficacy.
@nl
P2093
P1476
Flavones as colorectal cancer ...... -methylation enhances efficacy
@en
P2093
Andreas J Gescher
Robert G Britton
Stewart Sale
William P Steward
P304
P356
10.1158/1940-6207.CAPR-09-0081
P577
2009-07-28T00:00:00Z