Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene.
about
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stressExtreme-longevity mutations orchestrate silencing of multiple signaling pathwaysDevelopmental Drift and the Role of Wnt Signaling in AgingHuman longevity: Genetics or Lifestyle? It takes two to tangoGeroscience approaches to increase healthspan and slow agingGenetics, life span, health span, and the aging process in Caenorhabditis elegansDAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegansSlowing ageing by design: the rise of NAD(+) and sirtuin-activating compoundsDramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans.Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.Pathway-based factor analysis of gene expression data produces highly heritable phenotypes that associate with age.The genetics of ageing: insight from genome-wide approaches in invertebrate model organisms.Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance.The new biology of ageing.Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands.Mitochondrial changes in ageing Caenorhabditis elegans--what do we learn from superoxide dismutase knockouts?Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neuronsDAF-16 and Δ9 desaturase genes promote cold tolerance in long-lived Caenorhabditis elegans age-1 mutants.Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespanAn insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.A potential biochemical mechanism underlying the influence of sterol deprivation stress on Caenorhabditis elegans longevity.Remarkable longevity and stress resistance of nematode PI3K-null mutants.Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans.Lifespan extension by caloric restriction: an aspect of energy metabolism.DAF-16 target identification in C. elegans: past, present and future.Protein synthesis elongation factor EF-1 alpha expression and longevity in Drosophila melanogaster.Longevity and stress in Caenorhabditis elegansAge-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans.The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans.Invertebrates as model organisms for research on aging biologyDietary restriction and aging in rodents: a current view on its molecular mechanismsDiscovery of functional gene variants associated with human longevity: opportunities and challengesComparative endocrinology of aging and longevity regulationThe mysterious relationship between reproduction and longevity.Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegansFertility/longevity trade-offs under limiting-male conditions in mating populations of Caenorhabditis elegansPatterns of metabolic activity during aging of the wild type and longevity mutants of Caenorhabditis elegansPharmacological intervention in invertebrate aging.The role of stress in ageing: research on the nematode, Caenorhabditis elegans.Pharmacological lifespan extension of invertebrates
P2860
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P2860
Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Three mutants that extend both ...... legans, define the age-1 gene.
@en
Three mutants that extend both ...... legans, define the age-1 gene.
@nl
type
label
Three mutants that extend both ...... legans, define the age-1 gene.
@en
Three mutants that extend both ...... legans, define the age-1 gene.
@nl
prefLabel
Three mutants that extend both ...... legans, define the age-1 gene.
@en
Three mutants that extend both ...... legans, define the age-1 gene.
@nl
P356
P1476
Three mutants that extend both ...... legans, define the age-1 gene.
@en
P2093
Friedman DB
P304
P356
10.1093/GERONJ/43.4.B102
P577
1988-07-01T00:00:00Z