Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.
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Branched polyamines cure prion-infected neuroblastoma cellsConversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteinsPrionsSpontaneous generation of prion infectivity in fatal familial insomnia knockin micePhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Fatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob diseaseNMR structure of the bovine prion proteinAtomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion DiseaseChanging a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers.Glycosylation influences cross-species formation of protease-resistant prion protein.Elements modulating the prion species barrier and its passage consequencesMammalian prions: tolerance to sequence changes-how far?Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease.Human prion protein sequence elements impede cross-species chronic wasting disease transmission.Molecular Mechanisms of Chronic Wasting Disease Prion Propagation.Identification of two immunogenic domains of the prion protein--PrP--which activate class II-restricted T cells and elicit antibody responses against the native molecule.Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.Mapping of possible prion protein self-interaction domains using peptide arraysAccelerated high fidelity prion amplification within and across prion species barriers.Characteristics of 263K scrapie agent in multiple hamster speciesThe comprehensive native interactome of a fully functional tagged prion proteinConversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep scrapie in vivo.Cellular biology of prion diseases.Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein.Neurodegeneration in humans caused by prionsTransmission barriers for bovine, ovine, and human prions in transgenic mice.Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoformAffinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformationsSpecies-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence.Identification of two prion protein regions that modify scrapie incubation time.Efficient conversion of normal prion protein (PrP) by abnormal hamster PrP is determined by homology at amino acid residue 155.Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform.Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody.Cerebral amyloidosis in prion diseases.Prion protein genes and prion diseases: studies in transgenic mice.A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice.A molecular switch controls interspecies prion disease transmission in mice.Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9.Influence of Mabs on PrP(Sc) formation using in vitro and cell-free systemsMultiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform
P2860
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P2860
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Propagation of prions with art ...... expressing chimeric PrP genes.
@en
Propagation of prions with art ...... expressing chimeric PrP genes.
@nl
type
label
Propagation of prions with art ...... expressing chimeric PrP genes.
@en
Propagation of prions with art ...... expressing chimeric PrP genes.
@nl
prefLabel
Propagation of prions with art ...... expressing chimeric PrP genes.
@en
Propagation of prions with art ...... expressing chimeric PrP genes.
@nl
P2093
P1433
P1476
Propagation of prions with art ...... expressing chimeric PrP genes.
@en
P2093
P304
P356
10.1016/0092-8674(93)90275-U
P407
P577
1993-06-01T00:00:00Z