DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.
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Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspringHuman sperm sex chromosome disomy and sperm DNA damage assessed by the neutral comet assaySperm DNA integrity assays: diagnostic and prognostic challenges and implications in management of infertilityThe combined human sperm proteome: cellular pathways and implications for basic and clinical scienceNovel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentationA model for the control of DNA integrity by the sperm nuclear matrixAre sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?Oxidative stress and male reproductive healthSperm DNA oxidative damage and DNA adductsMammalian sperm nuclear organization: resiliencies and vulnerabilitiesThe molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognitionMouse spermatocytes express CYP2E1 and respond to acrylamide exposureTypes, causes, detection and repair of DNA fragmentation in animal and human sperm cellsSelection of functional human sperm with higher DNA integrity and fewer reactive oxygen speciesBulky DNA adducts in human sperm associated with semen parameters and sperm DNA fragmentation in infertile men: a cross-sectional study.Which isolated sperm abnormality is most related to sperm DNA damage in men presenting for infertility evaluation.Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality.Sperm DNA integrity and meiotic behavior assessment in an infertile male carrier of a 9qh+++ polymorphism.Sperm DNA fragmentation and oxidation are independent of malondialdheyde.Effect of overnight staining on the quality of flow cytometric sorted stallion sperm: comparison with tradtitional protocols.Sperm nuclear DNA fragmentation and chromatin structure in one-day-old ejaculated sperm.Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer.Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase.Optimization of microelectrophoresis to select highly negatively charged spermMechanisms and clinical correlates of sperm DNA damage.Antioxidant therapy in male infertility: fact or fiction?Flow cytometry for the assessment of animal sperm integrity and functionality: state of the artApoptosis and DNA damage in human spermatozoa.Should autism be considered a canary bird telling that Homo sapiens may be on its way to extinction?Assessment of chromatin maturity in human spermatozoa: useful aniline blue assay for routine diagnosis of male infertilityBiomarkers for early detection of malignant mesothelioma: diagnostic and therapeutic application.Sperm DNA and chromatin integrity in semen samples used for intrauterine insemination.Memoirs of an insult: sperm as a possible source of transgenerational epimutations and genetic instability.Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition.Are sperm chromatin and DNA defects relevant in the clinic?Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology.The source and significance of DNA damage in human spermatozoa; a commentary on diagnostic strategies and straw man fallacies.Assessing sperm chromatin and DNA damage: clinical importance and development of standards."Breaking news" from spermatids.TUNEL labeling with BrdUTP/anti-BrdUTP greatly underestimates the level of sperm DNA fragmentation in semen evaluation.
P2860
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P2860
DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
DNA damage in human spermatozo ...... a marker of oxidative stress.
@en
DNA damage in human spermatozo ...... a marker of oxidative stress.
@nl
type
label
DNA damage in human spermatozo ...... a marker of oxidative stress.
@en
DNA damage in human spermatozo ...... a marker of oxidative stress.
@nl
prefLabel
DNA damage in human spermatozo ...... a marker of oxidative stress.
@en
DNA damage in human spermatozo ...... a marker of oxidative stress.
@nl
P2093
P2860
P1476
DNA damage in human spermatozo ...... a marker of oxidative stress.
@en
P2093
Adam J Koppers
Andrew Hedges
Brett Nixon
Jane M Finnie
Laura K Thomson
Lisa A Mitchell
R John Aitken
P2860
P304
P356
10.1095/BIOLREPROD.109.076836
P407
P577
2009-06-03T00:00:00Z