PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity. - Wikidata - awgldk - TriplyDB

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

http://www.wikidata.org/entity/Q45998535

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells Fine-tuning multiprotein complexes using small molecules A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence Chemical genetic strategy for targeting protein kinases based on covalent complementarity Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1 Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Protein kinase C: poised to signal The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis A molecular switch for the orientation of epithelial cell polarization Conserved modular domains team up to latch-open active protein kinase Cα Protein kinase C-{delta} regulates the subcellular localization of Shc in H2O2-treated cardiomyocytes.An active kinase domain is required for retention of PKCθ at the T cell immunological synapse.Active site inhibitors protect protein kinase C from dephosphorylation and stabilize its mature form.ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.PDK1 in apical signaling endosomes participates in the rescue of the polarity complex atypical PKC by intermediate filaments in intestinal epithelia.Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways.Novel regulation of protein kinase C-η.Hsa-miR-449a genetic variant is associated with risk of gastric cancer in a Chinese population.The emerging role of protein kinase Cθ in cytoskeletal signaling.Heat shock proteins regulate activation-induced proteasomal degradation of the mature phosphorylated form of protein kinase C.Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F.Reduced Activity of Mutant Calcium-Dependent Protein Kinase 1 Is Compensated in Plasmodium falciparum through the Action of Protein Kinase G.Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.Occupational hazards: allosteric regulation of protein kinases through the nucleotide-binding pocket.Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases.Protein kinase C pharmacology: refining the toolbox.Pseudokinase drug intervention: a potentially poisoned chalice.The Multifunctional Protein Kinase C-ε in Cancer Development and Progression.Regulation of the cytokinesis cleavage furrow by PKCε.Molecular Control of Atypical Protein Kinase C: Tipping the Balance between Self-Renewal and Differentiation Phosphorylation of Tyr245 in the open-inhibited state of Abelson kinase does not induce downstream signaling.Cell-Specific PKM Isoforms Contribute to the Maintenance of Different Forms of Persistent Long-Term Synaptic Plasticity.Autophosphorylation of gatekeeper tyrosine by symbiosis receptor kinase.p120 catenin is a key effector of a Ras-PKCɛ oncogenic signaling axis.mTORC2 targets AGC kinases through Sin1-dependent recruitment.

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P2860

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

http://www.wikidata.org/entity/Q45998535

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年學術文章

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name

PKC maturation is promoted by ...... of intrinsic kinase activity.

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PKC maturation is promoted by ...... of intrinsic kinase activity.

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type

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PKC maturation is promoted by ...... of intrinsic kinase activity.

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PKC maturation is promoted by ...... of intrinsic kinase activity.

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prefLabel

PKC maturation is promoted by ...... of intrinsic kinase activity.

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PKC maturation is promoted by ...... of intrinsic kinase activity.

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P1433

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P1433

Nature Structural & Molecular Biology

P1476

PKC maturation is promoted by ...... of intrinsic kinase activity.

@en

P2093

Adrian T Saurin

http://www.w3.org/2001/XMLSchema#string

Angus J M Cameron

http://www.w3.org/2001/XMLSchema#string

Brenda Kostelecky

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Cristina Escribano

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Peter J Parker

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P2860

The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

The extended protein kinase C superfamily

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.

Crystal structure of an inactive Akt2 kinase domain

Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP-PNP

Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAP

Dephosphorylation of PKCdelta by protein phosphatase 2Ac and its inhibition by nucleotides

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

Specificity and mechanism of action of some commonly used protein kinase inhibitors

P2888

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624-630

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10.1038/NSMB.1606

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6

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16

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2009-05-24T00:00:00Z

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26237481

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1041008301

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19465915

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