Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers. - Wikidata - awgldk - TriplyDB

Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers.

Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers.

http://www.wikidata.org/entity/Q45999881

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Blood transcriptomics: applications in toxicology Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibrosis Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury Mining kidney toxicogenomic data by using gene co-expression modules Evaluation of putative biomarkers of nephrotoxicity after exposure to ochratoxin a in vivo and in vitro.An integrative model of multi-organ drug-induced toxicity prediction using gene-expression data.Qualitative evaluation of chromatographic data from quality control schemes using a support vector machine.High-resolution proteome/peptidome analysis of peptides and low-molecular-weight proteins in urine Use of transcriptomics in understanding mechanisms of drug-induced toxicity A high-throughput respirometric assay for mitochondrial biogenesis and toxicity.Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury.Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology.Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury.Evaluation of novel acute urinary rat kidney toxicity biomarker for subacute toxicity studies in preclinical trials.Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and -8 expression levels.Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity Mechanisms of acute kidney injury induced by experimental Lonomia obliqua envenomation.Recent successes in the identification, development, and qualification of translational biomarkers: the next generation of kidney injury biomarkers.Cell adhesion molecules in chemically-induced renal injury.Selenium-binding protein 1: a sensitive urinary biomarker to detect heavy metal-induced nephrotoxicity.Genomic-based biomarkers of drug-induced nephrotoxicity.Renal nucleoside transporters: physiological and clinical implications.Performance of urinary and gene expression biomarkers in detecting the nephrotoxic effects of melamine and cyanuric acid following diverse scenarios of co-exposure.Pathway analysis tools and toxicogenomics reference databases for risk assessment.Gene expression analysis reveals new possible mechanisms of vancomycin-induced nephrotoxicity and identifies gene markers candidates.Kidney Injury Molecule-1 (KIM-1): a specific and sensitive biomarker of kidney injury.Toxicogenomics and cross-species biomarker discovery: applications in drug discovery and safety assessment.Metabolomics for early detection of drug-induced kidney injury: review of the current status.Preclinical perspective of urinary biomarkers for the detection of nephrotoxicity: what we know and what we need to know.Urinary biomarkers in hexachloro-1:3-butadiene-induced acute kidney injury in the female Hanover Wistar rat; correlation of α-glutathione S-transferase, albumin and kidney injury molecule-1 with histopathology and gene expression.Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles.Identification of metabolomic biomarkers for drug-induced acute kidney injury in rats.Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether ("compound A") in rats.Comparative analysis of gene expression between renal cortex and papilla in nedaplatin-induced nephrotoxicity in rats.Normal ranges and variability of novel urinary renal biomarkers in Sprague-Dawley Rats: comparison of constitutive values between males and females and across assay platforms.Ellagic acid confers protection against gentamicin-induced oxidative damage, mitochondrial dysfunction and apoptosis-related nephrotoxicity.Potential role of poly(ADP-ribose) polymerase (PARP) activation in methotrexate-induced nephrotoxicity and tubular apoptosis.Evaluation of novel biomarkers in nephrotoxicity.

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P2860

Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers.

http://www.wikidata.org/entity/Q45999881

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Prediction of nephrotoxicant a ...... e toxicity-related biomarkers.

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Prediction of nephrotoxicant a ...... e toxicity-related biomarkers.

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Prediction of nephrotoxicant a ...... e toxicity-related biomarkers.

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Prediction of nephrotoxicant a ...... e toxicity-related biomarkers.

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Toxicologic Pathology

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Prediction of nephrotoxicant a ...... e toxicity-related biomarkers.

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Eric Galambos

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Laura Healy

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Michael B Bass

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Paul J Nordone

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Rong Hu

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Vincent D Fitzpatrick

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P2860

Cluster analysis and display of genome-wide expression patterns

Identification of putative gene based markers of renal toxicity

Knowledge-based analysis of microarray gene expression data by using support vector machines

The sodium phosphate cotransporter family SLC34

Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles

Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration

Microarrays and toxicology: the advent of toxicogenomics.

Discovering novel chemotherapeutic drugs for the third millennium.

Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors

Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: criteria, validation, strategies.

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