Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. - Wikidata - awgldk - TriplyDB

Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p.

Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p.

http://www.wikidata.org/entity/Q46016417

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Updates of mTOR inhibitors Rapamycin and mTOR kinase inhibitors mTOR kinase structure, mechanism and regulation Mcm2 phosphorylation and the response to replicative stress TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae.TOR1 and TOR2 have distinct locations in live cells Aup1-mediated regulation of Rtg3 during mitophagy Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses.The histone H3 lysine 56 acetylation pathway is regulated by target of rapamycin (TOR) signaling and functions directly in ribosomal RNA biogenesis Budding yeast greatwall and endosulfines control activity and spatial regulation of PP2A(Cdc55) for timely mitotic progression.Genome-wide screen of genes required for caffeine tolerance in fission yeast Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting Leucine signaling in the pathogenesis of type 2 diabetes and obesity Somatic Mutations in the MTOR gene cause focal cortical dysplasia type IIb.Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha.Regulation of multiple tip formation by caffeine in cellular slime molds A phenotypic profile of the Candida albicans regulatory network.Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae TOR-dependent control of autophagy: biting the hand that feeds Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage Hunger artists: yeast adapted to carbon limitation show trade-offs under carbon sufficiency Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds.Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.Botanical and phytochemical therapy of acne: a systematic review.Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphatase Activating mutations of TOR (target of rapamycin).Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases.Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance.Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae.Bicluster Sampled Coherence Metric (BSCM) provides an accurate environmental context for phenotype predictions.Both the autophagy and proteasomal pathways facilitate the Ubp3p-dependent depletion of a subset of translation and RNA turnover factors during nitrogen starvation in Saccharomyces cerevisiae.Genetic mapping of MAPK-mediated complex traits Across S. cerevisiae.Target of rapamycin (TOR) in nutrient signaling and growth control Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2.Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells Mechanisms regulating the protein kinases of Saccharomyces cerevisiae.The TOR complex 1 is a direct target of Rho1 GTPase.TOR under stress: targeting TORC1 by Rho1 GTPase A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress.Network-assisted target identification for haploinsufficiency and homozygous profiling screens.

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P2860

Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p.

http://www.wikidata.org/entity/Q46016417

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

@zh-my

2006年学术文章

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2006年學術文章

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2006年學術文章

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name

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

@en

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

@nl

type

label

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

@en

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

@nl

prefLabel

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

@en

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

@nl

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Journal of Biological Chemistry

P1476

Caffeine targets TOR complex I ...... B and kinase domains of Tor1p.

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P2093

Aaron Reinke

http://www.w3.org/2001/XMLSchema#string

Jenny C-Y Chen

http://www.w3.org/2001/XMLSchema#string

Sofia Aronova

http://www.w3.org/2001/XMLSchema#string

Ted Powers

http://www.w3.org/2001/XMLSchema#string

P2860

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

TOR signaling in growth and metabolism

Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast.

Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.

Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex.

Molecular organization of target of rapamycin complex 2.

TOR, a central controller of cell growth.

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31616-31626

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scholarly article

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10.1074/JBC.M603107200

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42

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P478

281

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2006-08-21T00:00:00Z

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16923813

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