Calpain 3 participates in sarcomere remodeling by acting upstream of the ubiquitin-proteasome pathway.
about
Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodelingAhnak1 abnormally localizes in muscular dystrophies and contributes to muscle vesicle releaseA new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-κB pathway in skeletal muscleCalpain 3 is a modulator of the dysferlin protein complex in skeletal muscleNovel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscleDown-regulation of MyoD by calpain 3 promotes generation of reserve cells in C2C12 myoblastsMyogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.Gene expression profiling in limb-girdle muscular dystrophy 2ANovel transcriptional profile in wrist muscles from cerebral palsy patients.Hsp27 associates with the titin filament system in heat-shocked zebrafish cardiomyocytes.Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94.Effect of nutrient restriction and re-feeding on calpain family genes in skeletal muscle of channel catfish (Ictalurus punctatus)Tearin' up my heart: proteolysis in the cardiac sarcomereAutolytic activation of calpain 3 proteinase is facilitated by calmodulin proteinRegulation of the M-cadherin-beta-catenin complex by calpain 3 during terminal stages of myogenic differentiationMolecular events and signalling pathways involved in skeletal muscle disuse-induced atrophy and the impact of countermeasures.Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H.Activation of Both the Calpain and Ubiquitin-Proteasome Systems Contributes to Septic Cardiomyopathy through Dystrophin Loss/Disruption and mTOR InhibitionMuscle Transcriptional Profile Based on Muscle Fiber, Mitochondrial Respiratory Activity, and Metabolic Enzymes.Impaired calcium calmodulin kinase signaling and muscle adaptation response in the absence of calpain 3Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.The NF-kappaB inhibitor curcumin blocks sepsis-induced muscle proteolysisAge-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis.Attenuated Ca(2+) release in a mouse model of limb girdle muscular dystrophy 2A.Serological muscle loss biomarkers: an overview of current concepts and future possibilitiesNatural history of LGMD2A for delineating outcome measures in clinical trialsImpaired regeneration in LGMD2A supported by increased PAX7-positive satellite cell content and muscle-specific microrna dysregulation.Animal models of muscular dystrophySMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpainCalpain activity and muscle wasting in sepsisRegulation of caspase-3 activity by insulin in skeletal muscle cells involves both PI3-kinase and MEK-1/2Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance.Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscleCardiac muscle ring finger-1 increases susceptibility to heart failure in vivo.Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy).Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks.No-dependent signaling pathways in unloaded skeletal muscle.Transcriptional pathways associated with skeletal muscle disuse atrophy in humans.Correlations between clinical severity, genotype and muscle pathology in limb girdle muscular dystrophy type 2A.Along signal paths: an empirical gene set approach exploiting pathway topology.
P2860
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P2860
Calpain 3 participates in sarcomere remodeling by acting upstream of the ubiquitin-proteasome pathway.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Calpain 3 participates in sarc ...... ubiquitin-proteasome pathway.
@en
Calpain 3 participates in sarc ...... ubiquitin-proteasome pathway.
@nl
type
label
Calpain 3 participates in sarc ...... ubiquitin-proteasome pathway.
@en
Calpain 3 participates in sarc ...... ubiquitin-proteasome pathway.
@nl
prefLabel
Calpain 3 participates in sarc ...... ubiquitin-proteasome pathway.
@en
Calpain 3 participates in sarc ...... ubiquitin-proteasome pathway.
@nl
P2093
P2860
P356
P1476
Calpain 3 participates in sarc ...... e ubiquitin-proteasome pathway
@en
P2093
Gayathri Venkatraman
Irina Kramerova
Melissa J Spencer
P2860
P304
P356
10.1093/HMG/DDI217
P577
2005-06-16T00:00:00Z