Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.
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Spatiotemporal Regulation of Nuclear Transport Machinery and Microtubule OrganizationMAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formationPaired arrangement of kinetochores together with microtubule pivoting and dynamics drive kinetochore capture in meiosis IThe kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-AAlp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism.Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.Meiotic nuclear movements in fission yeast are regulated by the transcription factor Mei4 downstream of a Cds1-dependent replication checkpoint pathwayLinked in: formation and regulation of microtubule attachments during chromosome segregation.Polo-like kinases: structural variations lead to multiple functions.Differentiating the roles of microtubule-associated proteins at meiotic kinetochores during chromosome segregation.An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation.Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast.Protein adaptation: mitotic functions for membrane trafficking proteins.
P2860
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P2860
Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.
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2013 nî lūn-bûn
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name
Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.
@en
Microtubules and Alp7-Alp14
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type
label
Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.
@en
Microtubules and Alp7-Alp14
@nl
prefLabel
Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.
@en
Microtubules and Alp7-Alp14
@nl
P2093
P2860
P356
P1433
P1476
Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation
@en
P2093
Masamitsu Sato
Masayuki Yamamoto
Naoyuki Okada
Takashi Toda
P2860
P2888
P304
P356
10.1038/NCB2782
P577
2013-06-16T00:00:00Z