Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.
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Epigenetic treatment of solid tumours: a review of clinical trialsEpigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: disease and treatmentsTrials with 'epigenetic' drugs: an updatePotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesDNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cellsProcaine Inhibits Osteo/Odontogenesis through Wnt/β-Catenin InactivationResponse to hydralazine-valproate in a patient with mycosis fungoidesA higher degree of expression of DNA methyl transferase 1 in cervical cancer is associated with poor survival outcome.A double-blind, placebo-controlled, randomized phase III trial of chemotherapy plus epigenetic therapy with hydralazine valproate for advanced cervical cancer. Preliminary results.Targeting DNA methylation for epigenetic therapy.DNA demethylating antineoplastic strategies: a comparative point of viewMIEN1 is tightly regulated by SINE Alu methylation in its promoter.DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge.Epigenetic regulation in myelodysplastic syndromes: implications for therapy.Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor.The promise and failures of epigenetic therapies for cancer treatmentHydralazine-valproate: a repositioned drug combination for the epigenetic therapy of cancer.Biological and biochemical modulation of DNA methylation.Developmental DNA methyltransferase inhibitors in the treatment of gynecologic cancers.Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.DNA Methyltransferase Inhibitors: Development and Applications.Induction of a trophoblast-like phenotype by hydralazine in the p19 embryonic carcinoma cell line.A DNA methyltransferase modulator inspired by peyssonenyne natural product structures.Rapid synthesis of new DNMT inhibitors derivatives of procainamide.Hydralazine-induced promoter demethylation enhances sarcoplasmic reticulum Ca2+ -ATPase and calcium homeostasis in cardiac myocytes.The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells.Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach.Docking of a novel DNA methyltransferase inhibitor identified from high-throughput screening: insights to unveil inhibitors in chemical databases.Chemoinformatics: a perspective from an academic setting in Latin America.N-Acetyltransferase 2 Genotype-Dependent N-Acetylation of Hydralazine in Human Hepatocytes.From natural products to drugs for epimutation computer-aided drug design.Pharmacokinetics of the Experimental Non-Nucleosidic DNA Methyl Transferase Inhibitor N-Phthalyl-L-Tryptophan (RG 108) in Rats.Regulation of Immune Function by Polyphenols.
P2860
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P2860
Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@en
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@nl
type
label
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@en
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@nl
prefLabel
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@en
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@nl
P2093
P356
P1433
P1476
Molecular modeling and molecul ...... human DNA methyltransferase 1.
@en
P2093
Alfonso Dueñas-González
Frank Lyko
Jose L Medina-Franco
Narender Singh
P304
P356
10.1002/CMDC.200900017
P577
2009-05-01T00:00:00Z