The Genetic Evolution of Melanoma from Precursor Lesions.
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Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical ImplicationsRecent advances in molecular genetics of melanoma progression: implications for diagnosis and treatmentMelanocortin 1 Receptor: Structure, Function, and RegulationCurrent concepts in the diagnosis and pathobiology of intraepithelial neoplasia: A review by organ systemThe Mole Mapper Study, mobile phone skin imaging and melanoma risk data collected using ResearchKitFunction and Clinical Implications of Long Non-Coding RNAs in Melanoma.Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulationClinicopathological features and prognosis of patients with de novo versus nevus-associated melanoma in Taiwan.Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathwaysGenetic characterization of Polish ccRCC patients: somatic mutation analysis of PBRM1, BAP1 and KDMC5, genomic SNP array analysis in tumor biopsy and preliminary results of chromosome aberrations analysis in plasma cell free DNAMatrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer.Phase II Study of Adjuvant Immunotherapy with the CSF-470 Vaccine Plus Bacillus Calmette-Guerin Plus Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor vs Medium-Dose Interferon Alpha 2B in Stages IIB, IIC, and III Cutaneous MelanomaThe genetic landscape of benign thyroid nodules revealed by whole exome and transcriptome sequencing.Genetic Mutations and Epigenetic Modifications: Driving Cancer and Informing Precision Medicine.The NF1 somatic mutational landscape in sporadic human cancers.Pathologists' diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility studyThe Warburg Effect: How Does it Benefit Cancer Cells?Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue.Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple MetastasesOptimized Prediction of Extreme Treatment Outcomes in Ovarian Cancer.Transforming Cancer Prevention through Precision Medicine and Immune-oncology.The Conundrum of Genetic "Drivers" in Benign Conditions.Shorter telomere length in Europeans than in Africans due to polygenetic adaptation.Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.Hepatic small vessel neoplasm, a rare infiltrative vascular neoplasm of uncertain malignant potential.Epigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analysesClustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies.Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse modelEpigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.Genetic and Epigenetic Alterations of TERT Are Associated with Inferior Outcome in Adolescent and Young Adult Patients with Melanoma.Germline variation at CDKN2A and associations with nevus phenotypes among members of melanoma families.Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model.The genomic landscape of cutaneous melanoma.Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes.Melanocytic nevi and melanoma: unraveling a complex relationship.SF3B1 and BAP1 mutations in blue nevus-like melanoma.The impact of melanoma genetics on treatment response and resistance in clinical and experimental studies.
P2860
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P2860
The Genetic Evolution of Melanoma from Precursor Lesions.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh-hant
name
The Genetic Evolution of Melanoma from Precursor Lesions.
@en
The Genetic Evolution of Melanoma from Precursor Lesions.
@nl
type
label
The Genetic Evolution of Melanoma from Precursor Lesions.
@en
The Genetic Evolution of Melanoma from Precursor Lesions.
@nl
prefLabel
The Genetic Evolution of Melanoma from Precursor Lesions.
@en
The Genetic Evolution of Melanoma from Precursor Lesions.
@nl
P2093
P50
P356
P1476
The Genetic Evolution of Melanoma from Precursor Lesions.
@en
P2093
A Hunter Shain
Alexander Gagnon
Alistair Robson
Aravindhan Sriharan
Beth Ruben
Corrado D'Arrigo
Ivanka Kovalyshyn
Jeffrey North
Laura Pincus
Reinhard Dummer
P304
P356
10.1056/NEJMOA1502583
P407
P577
2015-11-01T00:00:00Z