Computational strategies unravel and trace how liver disease changes hepatic drug disposition.
about
Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational modelsAgent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivityCompeting Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual ExperimentsA Multiscale Agent-Based in silico Model of Liver Fibrosis ProgressionAt the biological modeling and simulation frontier.Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity.Cloud computing and validation of expandable in silico liversDrug structure-transport relationshipsQuantitative Evaluation and Prediction of Drug Effects and Toxicological Risk Using Mechanistic Multiscale Models.Computational investigation of epithelial cell dynamic phenotype in vitro.Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage.
P2860
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P2860
Computational strategies unravel and trace how liver disease changes hepatic drug disposition.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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2008年學術文章
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name
Computational strategies unrav ...... nges hepatic drug disposition.
@en
Computational strategies unrav ...... nges hepatic drug disposition.
@nl
type
label
Computational strategies unrav ...... nges hepatic drug disposition.
@en
Computational strategies unrav ...... nges hepatic drug disposition.
@nl
prefLabel
Computational strategies unrav ...... nges hepatic drug disposition.
@en
Computational strategies unrav ...... nges hepatic drug disposition.
@nl
P2093
P356
P1476
Computational strategies unrav ...... nges hepatic drug disposition.
@en
P2093
C Anthony Hunt
Glen E P Ropella
Sean H J Kim
Sunwoo Park
P304
P356
10.1124/JPET.108.142497
P407
P577
2008-10-23T00:00:00Z