Paralysis and early death in cysteine string protein mutants of Drosophila.
about
Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosisJ protein mutations and resulting proteostasis collapseQuercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmissionSynaptic vesicle trafficking and Parkinson's diseaseMutations in DNAJC5, encoding cysteine-string protein alpha, cause autosomal-dominant adult-onset neuronal ceroid lipofuscinosisThe cysteine-string domain of the secretory vesicle cysteine-string protein is required for membrane targetingUNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assemblyRapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signalingPlasma membrane localization is required for RGS4 function in Saccharomyces cerevisiaeThe synaptic protein syntaxin1 is required for cellularization of Drosophila embryosIncreased synaptic microtubules and altered synapse development in Drosophila sec8 mutantsCSPα knockout causes neurodegeneration by impairing SNAP-25 functionThe synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degenerationNeto-mediated intracellular interactions shape postsynaptic composition at the Drosophila neuromuscular junctionThe Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in DrosophilaDrosophila Importin-α2 is involved in synapse, axon and muscle developmentGlia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debrisEnhancement of presynaptic calcium current by cysteine string proteinAn essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junctiondSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2.The dynamin-binding domains of Dap160/intersectin affect bulk membrane retrieval in synapses.A presynaptic endosomal trafficking pathway controls synaptic growth signalingSyndapin promotes formation of a postsynaptic membrane system in DrosophilaAbl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1.Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.Widespread changes in synaptic markers as a function of sleep and wakefulness in Drosophila.Drosophila rolling blackout displays lipase domain-dependent and -independent endocytic functions downstream of dynamin.Analysis of temperature-sensitive mutants reveals new genes involved in the courtship song of Drosophila.Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expressionVisualization of synaptic markers in the optic neuropils of Drosophila using a new constrained deconvolution method.The Wuerzburg hybridoma library against Drosophila brain.Hsp40 couples with the CSPalpha chaperone complex upon induction of the heat shock response.Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila.Interactions between proteins implicated in exocytosis and voltage-gated calcium channels.Immunocytochemical localization of synaptic proteins to photoreceptor synapses of Drosophila melanogasterMaintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutantsPhotoreceptor neurons find new synaptic targets when misdirected by overexpressing runt in DrosophilaPhosphomimetic mutation of cysteine string protein-α increases the rate of regulated exocytosis by modulating fusion pore dynamics in PC12 cells.Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis.
P2860
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P2860
Paralysis and early death in cysteine string protein mutants of Drosophila.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Paralysis and early death in cysteine string protein mutants of Drosophila.
@en
Paralysis and early death in cysteine string protein mutants of Drosophila.
@nl
type
label
Paralysis and early death in cysteine string protein mutants of Drosophila.
@en
Paralysis and early death in cysteine string protein mutants of Drosophila.
@nl
prefLabel
Paralysis and early death in cysteine string protein mutants of Drosophila.
@en
Paralysis and early death in cysteine string protein mutants of Drosophila.
@nl
P2093
P356
P1433
P1476
Paralysis and early death in cysteine string protein mutants of Drosophila.
@en
P2093
P304
P356
10.1126/SCIENCE.8310297
P407
P577
1994-02-01T00:00:00Z