Retinoid X receptor (RXR) ligands activate the human 25-hydroxyvitamin D3-24-hydroxylase promoter via RXR heterodimer binding to two vitamin D-responsive elements and elicit additive effects with 1,25-dihydroxyvitamin D3.
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Repressors of androgen and progesterone receptor actionHigh-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cellsPossible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalaciaA novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expressionCyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator.New insights into the function and regulation of vitamin D target proteins.Regulation of cytochrome P450 (CYP) genes by nuclear receptors.Anticancer activity of VDR-coregulator inhibitor PS121912.Regulation of progesterone receptor activity by cyclin dependent kinases 1 and 2 occurs in part by phosphorylation of the SRC-1 carboxyl-terminus.1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A.Suppression of death receptor-mediated apoptosis by 1,25-dihydroxyvitamin D3 revealed by microarray analysis.Vitamin D metabolism: new concepts and clinical implicationsAT1R blockade in adverse milieus: role of SMRT and corepressor complexes.The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity.Downregulation of host tryptophan-aspartate containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in human macrophage model.The vitamin D3 transcriptomic response in skin cells derived from the Atlantic bottlenose dolphin.1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498.All-trans retinoic acid converts E2F into a transcriptional suppressor and inhibits the growth of normal human bronchial epithelial cells through a retinoic acid receptor- dependent signaling pathway.Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydroThe vitamin D response element-binding protein. A novel dominant-negative regulator of vitamin D-directed transactivation.MDM2 binds and inhibits vitamin D receptor.Targeted disruption of the p160 coactivator interface of androgen receptor (AR) selectively inhibits AR activity in both androgen-dependent and castration-resistant AR-expressing prostate cancer cells.Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding.Cloning, sequencing, and functional characterization of the vitamin D receptor in vitamin D-resistant New World primates.The inverse association between serum 25-hydroxyvitamin D and mortality may be modified by vitamin A status and use of vitamin A supplements.The impact of methylmercury on 1,25-dihydroxyvitamin D3-induced transcriptomic responses in dolphin skin cells.Integration of hormone signaling in the regulation of human 25(OH)D3 24-hydroxylase transcription.
P2860
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P2860
Retinoid X receptor (RXR) ligands activate the human 25-hydroxyvitamin D3-24-hydroxylase promoter via RXR heterodimer binding to two vitamin D-responsive elements and elicit additive effects with 1,25-dihydroxyvitamin D3.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@en
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@nl
type
label
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@en
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@nl
prefLabel
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@en
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@nl
P2093
P2860
P356
P1476
Retinoid X receptor (RXR) liga ...... with 1,25-dihydroxyvitamin D3.
@en
P2093
P2860
P304
19027-19034
P356
10.1074/JBC.272.30.19027
P407
P577
1997-07-01T00:00:00Z