Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output gene Magel2.
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3-dimensional imaging modalities for phenotyping genetically engineered miceMagel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in miceUSP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental DisorderIn vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brainThe metabolic phenotype of Prader-Willi syndrome (PWS) in childhood: heightened insulin sensitivity relative to body mass index.Placental protection of the fetal brain during short-term food deprivation.Impaired hypothalamic regulation of endocrine function and delayed counterregulatory response to hypoglycemia in Magel2-null mice.Zebrafish Models of Prader-Willi Syndrome: Fast Track to Pharmacotherapeutics.Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome.Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite.Leptin signaling defects in a mouse model of Prader-Willi syndrome: An orphan genetic obesity syndrome no more?Epigenetics and brain evolution.Genetic diseases: congenital central hypoventilation, Rett, and Prader-Willi syndromes.What Gene Mutations Affect Serotonin in Mice?Distinct transcriptomes define rostral and caudal serotonin neurons.Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay.A Comprehensive Guide to the MAGE Family of Ubiquitin Ligases.Autism spectrum disorder: neuropathology and animal models.Magel2-null mice are hyper-responsive to setmelanotide, a melanocortin 4 receptor agonist.Loss of Magel2 impairs the development of hypothalamic Anorexigenic circuits.Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice.Prader-Willi Syndrome and Schaaf-Yang Syndrome: Neurodevelopmental Diseases Intersecting at the MAGEL2 Gene.Imprinting analysis of porcine MAGEL2 gene in two fetal stages and association analysis with carcass traits.Recommendations for the investigation of animal models of Prader-Willi syndrome.Magel2 knockout mice manifest altered social phenotypes and a deficit in preference for social novelty.The Prader-Willi syndrome proteins MAGEL2 and necdin regulate leptin receptor cell surface abundance through ubiquitination pathways.Loss of Necdin impairs myosin activation and delays cell polarization.Progressive postnatal decline in leptin sensitivity of arcuate hypothalamic neurons in the Magel2-null mouse model of Prader-Willi syndrome.Neuroanatomical Phenotypes Are Consistent With Autism-Like Behavioral Phenotypes in the 15q11-13 Duplication Mouse Model.Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus.Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes.Territorial Behavior and Social Stability in the Mouse Require Correct Expression of Imprinted Cdkn1c.
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P2860
Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output gene Magel2.
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2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-hans
2009年学术文章
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name
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@en
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@nl
type
label
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@en
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@nl
prefLabel
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@en
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@nl
P2093
P2860
P356
P1476
Regionally reduced brain volum ...... ian rhythm output gene Magel2.
@en
P2093
Erin M Kwolek
Jocelyn M Bischof
Matthijs van Eede
R Mark Henkelman
Rebecca E Mercer
P2860
P304
P356
10.1002/AJMG.B.30934
P577
2009-12-01T00:00:00Z