Production, quality control, stability and pharmacotoxicity of cGMP-produced Plasmodium falciparum AMA1 FVO strain ectodomain expressed in Pichia pastoris.
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Vaccination with Plasmodium knowlesi AMA1 formulated in the novel adjuvant co-vaccine HT™ protects against blood-stage challenge in rhesus macaquesStructural and Functional Insights into the Malaria Parasite Moving Junction ComplexProduction, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic VariationHumoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adultsMeasurement of the plasma levels of antibodies against the polymorphic vaccine candidate apical membrane antigen 1 in a malaria-exposed populationImmunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbitsGeneration of humoral immune responses to multi-allele PfAMA1 vaccines; effect of adjuvant and number of component alleles on the breadth of responseHumoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity.Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02.Protection of Malian children from clinical malaria is associated with recognition of multiple antigens.Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection.Hotspots of Malaria Transmission in the Peruvian Amazon: Rapid Assessment through a Parasitological and Serological Survey.Diversity covering AMA1-MSP119 fusion proteins as malaria vaccines.Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail.Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in BandiagaraAcquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors.Cross-reactivity between apical membrane antgen 1 and rhoptry neck protein 2 in P. vivax and P. falciparum: A structural and binding studyVariations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana.Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production in Pichia pastoris by the identification and removal of protease cleavage sites.Down selecting adjuvanted vaccine formulations: a comparative method for harmonized evaluation.Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits.Production, quality control, stability, and potency of cGMP-produced RH5.1 protein vaccine expressed in S2 cells
P2860
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P2860
Production, quality control, stability and pharmacotoxicity of cGMP-produced Plasmodium falciparum AMA1 FVO strain ectodomain expressed in Pichia pastoris.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Production, quality control, s ...... expressed in Pichia pastoris.
@en
Production, quality control, s ...... expressed in Pichia pastoris.
@nl
type
label
Production, quality control, s ...... expressed in Pichia pastoris.
@en
Production, quality control, s ...... expressed in Pichia pastoris.
@nl
prefLabel
Production, quality control, s ...... expressed in Pichia pastoris.
@en
Production, quality control, s ...... expressed in Pichia pastoris.
@nl
P2093
P1433
P1476
Production, quality control, s ...... expressed in Pichia pastoris.
@en
P2093
Alan W Thomas
Clemens H M Kocken
Doriano Cingolani
Florence Xhonneux
Margarita Jurado
Michele Haumont
Odile Leroy
Pascale Cheront
Soren Jepsen
P304
P356
10.1016/J.VACCINE.2008.08.055
P407
P577
2008-09-17T00:00:00Z