Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: a potential role in calcium buffering and sarcolemmal stability.

Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: a potential role in calcium buffering and sarcolemmal stability.

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http://www.wikidata.org/entity/Q46161936
Genetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophyLong-term blocking of calcium channels in mdx mice results in differential effects on heart and skeletal muscleQuantitative proteomic analysis reveals metabolic alterations, calcium dysregulation, and increased expression of extracellular matrix proteins in laminin α2 chain-deficient muscle.Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease.Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane.Early manifestation of alteration in cardiac function in dystrophin deficient mdx mouse using 3D CMR tagging.Dysregulation of calcium homeostasis in muscular dystrophies.Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice.P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatmentOverexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction-induced damage.Diltiazem improves contractile properties of skeletal muscle in dysferlin-deficient BLAJ mice, but does not reduce contraction-induced muscle damage.
P2860

Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: a potential role in calcium buffering and sarcolemmal stability.

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http://www.wikidata.org/entity/Q46161936
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2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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Diltiazem and verapamil protec ...... ing and sarcolemmal stability.
@en
Diltiazem and verapamil protec ...... ing and sarcolemmal stability.
@nl
type
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Diltiazem and verapamil protec ...... ing and sarcolemmal stability.
@en
Diltiazem and verapamil protec ...... ing and sarcolemmal stability.
@nl
prefLabel
Diltiazem and verapamil protec ...... ing and sarcolemmal stability.
@en
Diltiazem and verapamil protec ...... ing and sarcolemmal stability.
@nl
P1433
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P2860
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Diltiazem and verapamil protec ...... ring and sarcolemmal stability
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698