Cytoplasmic chromatin triggers inflammation in senescence and cancer. - Wikidata - awgldk - TriplyDB

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

http://www.wikidata.org/entity/Q46165767

about

Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug?ER stress signaling promotes the survival of cancer 'persister cells' tolerant to EGFR tyrosine kinase inhibitors.Cytosolic sensing of immuno-stimulatory DNA, the enemy within.Bypassing Border Control: Nuclear Envelope Rupture in Disease.Senescence and aging: Causes, consequences, and therapeutic avenues.Emerging roles of extracellular vesicles in cellular senescence and aging.Perturbing mitosis for anti-cancer therapy: is cell death the only answer?Nuclear envelope rupture: little holes, big openings.Chromosomal instability drives metastasis through a cytosolic DNA response.PARP1 depletion induces RIG-I-dependent signaling in human cancer cells.STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection.Mechanisms and functions of cellular senescence.Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING.Epigenomes in Cardiovascular Disease.Cytosolic Genomic DNA functions as a Natural Antisense.Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review.The extent of liver injury determines hepatocyte fate toward senescence or cancer.Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis.Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy Tetraploidy in cancer and its possible link to aging FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage Ageing, Cellular Senescence and Neurodegenerative Disease

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Cytoplasmic chromatin triggers inflammation in senescence and cancer.

http://www.wikidata.org/entity/Q46165767

description

2017 nî lūn-bûn

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2017年の論文

@ja

2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@en

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@nl

type

label

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@en

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@nl

prefLabel

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@en

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@nl

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P1476

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

@en

P2093

Benjamin A Garcia

http://www.w3.org/2001/XMLSchema#string

Caiyue Xu

http://www.w3.org/2001/XMLSchema#string

Glen N Barber

http://www.w3.org/2001/XMLSchema#string

Jiajun Zhu

http://www.w3.org/2001/XMLSchema#string

Johayra Simithy

http://www.w3.org/2001/XMLSchema#string

John T Seykora

http://www.w3.org/2001/XMLSchema#string

K M Ahasan Al Tanim

http://www.w3.org/2001/XMLSchema#string

Kanad Ghosh

http://www.w3.org/2001/XMLSchema#string

Klaus H Kaestner

http://www.w3.org/2001/XMLSchema#string

Maria Grazia Vizioli

http://www.w3.org/2001/XMLSchema#string

P2860

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

STING: infection, inflammation and cancer

Chromothripsis from DNA damage in micronuclei.

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

The complex language of chromatin regulation during transcription

Autophagy mediates degradation of nuclear lamina

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Lysosome-mediated processing of chromatin in senescence.

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402-406

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scholarly article

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10.1038/NATURE24050

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P433

7676

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550

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Shelley L. Berger

Kirk J Wangensteen

Julia E Kieckhaefer

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2017-10-04T00:00:00Z

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28976970

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5850938

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