Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
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Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.Urokinase-type plasminogen activator (uPA) induces pulmonary microvascular endothelial permeability through low density lipoprotein receptor-related protein (LRP)-dependent activation of endothelial nitric-oxide synthase.Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regenerationProteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites.IMD-4690, a novel specific inhibitor for plasminogen activator inhibitor-1, reduces allergic airway remodeling in a mouse model of chronic asthma via regulating angiogenesis and remodeling-related mediatorsAssociation of SERPINE2 with asthmaUrokinase plasminogen activator regulates pulmonary arterial contractility and vascular permeability in miceRole of epithelial sodium channels in the regulation of lung fluid homeostasisPlasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone.Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells.Involvement of urokinase in cigarette smoke extract-induced epithelial-mesenchymal transition in human small airway epithelial cells.Intestinal epithelial cell-derived integrin αβ6 plays an important role in the induction of regulatory T cells and inhibits an antigen-specific Th2 response.Regulation of airway contractility by plasminogen activators through N-methyl-D-aspartate receptor-1.Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling.Regulation of epithelial sodium channels in urokinase plasminogen activator deficiencyuPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium.
P2860
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P2860
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@en
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@nl
type
label
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@en
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@nl
prefLabel
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@en
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@nl
P2093
P2860
P1476
Inhalation of urokinase-type p ...... ling in a murine asthma model.
@en
P2093
Emi Kuramoto
Kazuyuki Kobayashi
Masatsugu Yamamoto
Richard H Simon
Teruaki Nishiuma
Thomas H Sisson
Yasuhiro Funada
Yoshihiro Nishimura
Yoshikazu Kotani
P2860
P304
P356
10.1152/AJPLUNG.90434.2008
P577
2008-12-19T00:00:00Z