Genetic background controls tumor development in PTEN-deficient mice.
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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in miceTransgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cellsReport on the use of non-clinical studies in the regulatory evaluation of oncology drugsBrca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesisFoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasisAKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung CancerThe synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs.Allele-specific tumor spectrum in pten knockin micePTEN-deficient tumors depend on AKT2 for maintenance and survival.Mouse models of endocrine tumours.Dietary energy balance modulates prostate cancer progression in Hi-Myc miceThe PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner.Sprouty genes function in suppression of prostate tumorigenesisCowden syndrome and Bannayan Riley Ruvalcaba syndrome represent one condition with variable expression and age-related penetrance: results of a clinical study of PTEN mutation carriers.Mitochondrial DNA mutations in mutator mice confer respiration defects and B-cell lymphoma development.Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice.Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromesSlow disease progression in a C57BL/6 pten-deficient mouse model of prostate cancer.A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNALoss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse modelHaploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcomaPten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo.Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice.Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways.Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development.Tumor spectrum, tumor latency and tumor incidence of the Pten-deficient mice.Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma.Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.Genetic background influences murine prostate gene expression: implications for cancer phenotypes.Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndromePTEN, more than the AKT pathway.An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasiasRecent progress in mouse models for tumor suppressor genes and its implications in human cancer.PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilizationDeletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.Expression of a Y-located human proto-oncogene TSPY in a transgenic mouse model of prostate cancer.Lung microRNA: from development to disease.
P2860
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P2860
Genetic background controls tumor development in PTEN-deficient mice.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Genetic background controls tumor development in PTEN-deficient mice.
@en
Genetic background controls tumor development in PTEN-deficient mice.
@nl
type
label
Genetic background controls tumor development in PTEN-deficient mice.
@en
Genetic background controls tumor development in PTEN-deficient mice.
@nl
prefLabel
Genetic background controls tumor development in PTEN-deficient mice.
@en
Genetic background controls tumor development in PTEN-deficient mice.
@nl
P2093
P1433
P1476
Genetic background controls tumor development in PTEN-deficient mice
@en
P2093
Dan Freeman
George Thomas
Hilda Martinez-Diaz
Nathalie Kertesz
Nora Rozengurt
Ralf Lesche
Shungyou Wang
P304
P356
10.1158/0008-5472.CAN-05-4143
P407
P50
P577
2006-07-01T00:00:00Z