The disulfide relay system of mitochondria is required for the biogenesis of mitochondrial Ccs1 and Sod1.
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Mechanisms of mutant SOD1 induced mitochondrial toxicity in amyotrophic lateral sclerosisStructure of the Human Sulfhydryl Oxidase Augmenter of Liver Regeneration and Characterization of a Human Mutation Causing an Autosomal Recessive Myopathy,Widespread dual targeting of proteins in land plants: when, where, how and why.Mdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formationCopper metallochaperonesA novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding.Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomesRedox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo.Mitochondrial dysfunction and intracellular calcium dysregulation in ALSSOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse.Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G)Mitochondrial Ccs1 contains a structural disulfide bond crucial for the import of this unconventional substrate by the disulfide relay systemProtein folding as a driving force for dual protein targeting in eukaryotesThe MIA pathway: a key regulator of mitochondrial oxidative protein folding and biogenesis.An Adaptation to Low Copper in Candida albicans Involving SOD Enzymes and the Alternative Oxidase.Ganoderma Lucidum polysaccharides protect against MPP(+) and rotenone-induced apoptosis in primary dopaminergic cell cultures through inhibiting oxidative stress.Augmenter of liver regeneration: substrate specificity of a flavin-dependent oxidoreductase from the mitochondrial intermembrane space.The right to choose: multiple pathways for activating copper,zinc superoxide dismutase.The power of yeast to model diseases of the powerhouse of the cell.Metal acquisition and availability in the mitochondria.Disulfide formation in the ER and mitochondria: two solutions to a common process.Disulphide bond formation in the intermembrane space of mitochondria.Import, maturation, and function of SOD1 and its copper chaperone CCS in the mitochondrial intermembrane space.Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis.SOD1 and mitochondria in ALS: a dangerous liaison.Mitochondrial disulfide relay: redox-regulated protein import into the intermembrane space.Oxidative folding in the mitochondrial intermembrane space in human health and disease.Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-mediated Inhibition of Mitochondrial Respiration.Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol.Oxygen-dependent activation of Cu,Zn-superoxide dismutase-1.Cytosolic redox components regulate protein homeostasis via additional localisation in the mitochondrial intermembrane space.Disulfide bond formation in yeast NAD+-specific isocitrate dehydrogenase.The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1.Erv1 of Arabidopsis thaliana can directly oxidize mitochondrial intermembrane space proteins in the absence of redox-active Mia40.A single-cysteine mutant and chimeras of essential Leishmania Erv can complement the loss of Erv1 but not of Mia40 in yeast.Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.Activation of Mitochondrial Protein Phosphatase SLP2 by MIA40 Regulates Seed Germination.Superoxide dismutase-1 and other proteins in inclusions from transgenic amyotrophic lateral sclerosis model mice.Human copper chaperone for superoxide dismutase 1 mediates its own oxidation-dependent import into mitochondria.
P2860
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P2860
The disulfide relay system of mitochondria is required for the biogenesis of mitochondrial Ccs1 and Sod1.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@en
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@nl
type
label
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@en
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@nl
prefLabel
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@en
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@nl
P2093
P1476
The disulfide relay system of ...... f mitochondrial Ccs1 and Sod1.
@en
P2093
Barbara Grumbt
Silvia Reddehase
Walter Neupert
P304
P356
10.1016/J.JMB.2008.10.088
P407
P577
2008-11-07T00:00:00Z