Crystal Structure of an LSD-Bound Human Serotonin Receptor.
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Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects.Return of the lysergamides. Part III: Analytical characterization of N6 -ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P-ETH-LAD).Arresting the Development of Addiction: The Role of β-Arrestin 2 in Drug Abuse.How Ligands Illuminate GPCR Molecular Pharmacology.Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs.The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand.Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody.D4 dopamine receptor high-resolution structures enable the discovery of selective agonists.Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775).Biased signalling: from simple switches to allosteric microprocessors.A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?Current and Future Challenges in GPCR Drug Discovery.Divergent Spatiotemporal Interaction of Angiotensin Receptor Blocking Drugs with Angiotensin Type 1 Receptor.Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.A kinetic view of GPCR allostery and biased agonism.Modulating the Serotonin Receptor Spectrum of Pulicatin Natural Products.Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50.Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist.In silico studies targeting G-protein coupled receptors for drug research against Parkinson's disease.Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design.Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes.Identification of natural products as novel ligands for the human 5-HT2C receptor.G protein-coupled receptors: the evolution of structural insight.Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategyPsychedelic-Assisted Psychotherapy: A Paradigm Shift in Psychiatric Research and DevelopmentExploring Halogen Bonds in 5-Hydroxytryptamine 2B Receptor-Ligand InteractionsHow the ubiquitous GPCR receptor family selectively activates signalling pathways
P2860
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P2860
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
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2017年學術文章
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2017年學術文章
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name
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@en
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@nl
type
label
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@en
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@nl
prefLabel
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@en
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@nl
P2093
P2860
P1433
P1476
Crystal Structure of an LSD-Bound Human Serotonin Receptor.
@en
P2093
A J Venkatakrishnan
Anat Levit
Brian K Shoichet
Bryan L Roth
Daniel Wacker
David E Nichols
John D McCorvy
Katherine Lansu
Robin M Betz
Ron O Dror
P2860
P304
377-389.e12
P356
10.1016/J.CELL.2016.12.033
P407
P577
2017-01-01T00:00:00Z